Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic

Abstract The toxic metalloid arsenic has been environmentally ubiquitous since life first arose nearly four billion years ago and presents a challenge for the survival of all living organisms. Its bioavailability has varied dramatically over the history of life on Earth. As life spread, biogeochemic...

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Autores principales:	Song-Can Chen, Guo-Xin Sun, Barry P. Rosen, Si-Yu Zhang, Ye Deng, Bo-Kai Zhu, Christopher Rensing, Yong-Guan Zhu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7ccd565adb4a4836853b2afb7e2c6a8b
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spelling	oai:doaj.org-article:7ccd565adb4a4836853b2afb7e2c6a8b2021-12-02T11:53:10ZRecurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic10.1038/s41598-017-08313-22045-2322https://doaj.org/article/7ccd565adb4a4836853b2afb7e2c6a8b2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08313-2https://doaj.org/toc/2045-2322Abstract The toxic metalloid arsenic has been environmentally ubiquitous since life first arose nearly four billion years ago and presents a challenge for the survival of all living organisms. Its bioavailability has varied dramatically over the history of life on Earth. As life spread, biogeochemical and climate changes cyclically increased and decreased bioavailable arsenic. To elucidate the history of arsenic adaptation across the tree of life, we reconstructed the phylogeny of the arsM gene that encodes the As(III) S-adenosylmethionine (SAM) methyltransferase. Our results suggest that life successfully moved into arsenic-rich environments in the late Archean Eon and Proterozoic Eon, respectively, by the spread of arsM genes. The arsM genes of bacterial origin have been transferred to other kingdoms of life on at least six occasions, and the resulting domesticated arsM genes promoted adaptation to environmental arsenic. These results allow us to peer into the history of arsenic adaptation of life on our planet and imply that dissemination of genes encoding diverse adaptive functions to toxic chemicals permit adaptation to changes in concentrations of environmental toxins over evolutionary history.Song-Can ChenGuo-Xin SunBarry P. RosenSi-Yu ZhangYe DengBo-Kai ZhuChristopher RensingYong-Guan ZhuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Song-Can Chen Guo-Xin Sun Barry P. Rosen Si-Yu Zhang Ye Deng Bo-Kai Zhu Christopher Rensing Yong-Guan Zhu Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic
description	Abstract The toxic metalloid arsenic has been environmentally ubiquitous since life first arose nearly four billion years ago and presents a challenge for the survival of all living organisms. Its bioavailability has varied dramatically over the history of life on Earth. As life spread, biogeochemical and climate changes cyclically increased and decreased bioavailable arsenic. To elucidate the history of arsenic adaptation across the tree of life, we reconstructed the phylogeny of the arsM gene that encodes the As(III) S-adenosylmethionine (SAM) methyltransferase. Our results suggest that life successfully moved into arsenic-rich environments in the late Archean Eon and Proterozoic Eon, respectively, by the spread of arsM genes. The arsM genes of bacterial origin have been transferred to other kingdoms of life on at least six occasions, and the resulting domesticated arsM genes promoted adaptation to environmental arsenic. These results allow us to peer into the history of arsenic adaptation of life on our planet and imply that dissemination of genes encoding diverse adaptive functions to toxic chemicals permit adaptation to changes in concentrations of environmental toxins over evolutionary history.
format	article
author	Song-Can Chen Guo-Xin Sun Barry P. Rosen Si-Yu Zhang Ye Deng Bo-Kai Zhu Christopher Rensing Yong-Guan Zhu
author_facet	Song-Can Chen Guo-Xin Sun Barry P. Rosen Si-Yu Zhang Ye Deng Bo-Kai Zhu Christopher Rensing Yong-Guan Zhu
author_sort	Song-Can Chen
title	Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic
title_short	Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic
title_full	Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic
title_fullStr	Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic
title_full_unstemmed	Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic
title_sort	recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7ccd565adb4a4836853b2afb7e2c6a8b
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Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic

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