Price trends of reimbursed oncological drugs in Switzerland in 2005-2019: A descriptive analysis.

Increasing oncological treatment costs are a major global concern with the risk of entailing two-tiered health care. Among cost determining factors is the price of individual drugs. In recognition of the central role of this factor, we present a comprehensive overview of the development of monthly p...

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Autores principales: Yael Rachamin, Christoph Jakob Ackermann, Oliver Senn, Thomas Grischott
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Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/7cceb14eaa2541c6b333e1e614f3fbb9
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spelling oai:doaj.org-article:7cceb14eaa2541c6b333e1e614f3fbb92021-12-02T20:13:04ZPrice trends of reimbursed oncological drugs in Switzerland in 2005-2019: A descriptive analysis.1932-620310.1371/journal.pone.0259936https://doaj.org/article/7cceb14eaa2541c6b333e1e614f3fbb92021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0259936https://doaj.org/toc/1932-6203Increasing oncological treatment costs are a major global concern with the risk of entailing two-tiered health care. Among cost determining factors is the price of individual drugs. In recognition of the central role of this factor, we present a comprehensive overview of the development of monthly prices of oncological drugs introduced over the last 15 years in Switzerland. We identified all oncological drugs newly reimbursed by mandatory health insurance in 2005-2019, and searched public repositories for their package prices, indications with approval dates, and treatment regimens for the calculation of (indication-specific) monthly prices. We found 81 products covering 77 different substances (39.5% protein kinase inhibitors, 21.0% monoclonal antibodies). Most indications related to the topography "blood", followed by "lung and thorax" and "digestive tract". From 2005-2009 to 2015-2019, the median monthly product price over all distinct indications of all products decreased by 7.56% (CHF 5,699 [interquartile range 4,483-7,321] to CHF 5,268 [4,19-6,967]), whereas it increased by 73.7% for monoclonal antibodies. In December 2019, six products had monthly prices over CHF 10,000, all approved for hematological or dermatological cancers. Our analysis suggests that individual price developments of oncological drugs are presently not the major driver of rising cancer treatment costs. However, rising launch prices of some new, mostly hematological drugs are of concern and require continued monitoring.Yael RachaminChristoph Jakob AckermannOliver SennThomas GrischottPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11, p e0259936 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Yael Rachamin
Christoph Jakob Ackermann
Oliver Senn
Thomas Grischott
Price trends of reimbursed oncological drugs in Switzerland in 2005-2019: A descriptive analysis.
description Increasing oncological treatment costs are a major global concern with the risk of entailing two-tiered health care. Among cost determining factors is the price of individual drugs. In recognition of the central role of this factor, we present a comprehensive overview of the development of monthly prices of oncological drugs introduced over the last 15 years in Switzerland. We identified all oncological drugs newly reimbursed by mandatory health insurance in 2005-2019, and searched public repositories for their package prices, indications with approval dates, and treatment regimens for the calculation of (indication-specific) monthly prices. We found 81 products covering 77 different substances (39.5% protein kinase inhibitors, 21.0% monoclonal antibodies). Most indications related to the topography "blood", followed by "lung and thorax" and "digestive tract". From 2005-2009 to 2015-2019, the median monthly product price over all distinct indications of all products decreased by 7.56% (CHF 5,699 [interquartile range 4,483-7,321] to CHF 5,268 [4,19-6,967]), whereas it increased by 73.7% for monoclonal antibodies. In December 2019, six products had monthly prices over CHF 10,000, all approved for hematological or dermatological cancers. Our analysis suggests that individual price developments of oncological drugs are presently not the major driver of rising cancer treatment costs. However, rising launch prices of some new, mostly hematological drugs are of concern and require continued monitoring.
format article
author Yael Rachamin
Christoph Jakob Ackermann
Oliver Senn
Thomas Grischott
author_facet Yael Rachamin
Christoph Jakob Ackermann
Oliver Senn
Thomas Grischott
author_sort Yael Rachamin
title Price trends of reimbursed oncological drugs in Switzerland in 2005-2019: A descriptive analysis.
title_short Price trends of reimbursed oncological drugs in Switzerland in 2005-2019: A descriptive analysis.
title_full Price trends of reimbursed oncological drugs in Switzerland in 2005-2019: A descriptive analysis.
title_fullStr Price trends of reimbursed oncological drugs in Switzerland in 2005-2019: A descriptive analysis.
title_full_unstemmed Price trends of reimbursed oncological drugs in Switzerland in 2005-2019: A descriptive analysis.
title_sort price trends of reimbursed oncological drugs in switzerland in 2005-2019: a descriptive analysis.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/7cceb14eaa2541c6b333e1e614f3fbb9
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AT oliversenn pricetrendsofreimbursedoncologicaldrugsinswitzerlandin20052019adescriptiveanalysis
AT thomasgrischott pricetrendsofreimbursedoncologicaldrugsinswitzerlandin20052019adescriptiveanalysis
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