Iodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis

Background: Despite current policies of salt iodination, iodine deficiency is still a global public health problem, especially in women. So far, conflicting evidence has been suggested for the prevalence of iodine deficiency in Brazil. Objective: To estimate the prevalence of iodine deficiency and...

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Autores principales:	Rosa Camila Lucchetta, Ana Luísa Rodriguez Gini, Sophia de Andrade Cavicchioli, Marcela Forgerini, Fabiana Rossi Varallo, Mariane Nunes de Nadai, Fernando Fernandez-Llimós, Patricia de Carvalho Mastroianni
Formato:	article
Lenguaje:	EN
Publicado:	Universidad de Antioquia 2021
Materias:	Iodine deficiency Prevalence study Nutritional Epidemiology Maternal Nutrition Women's Health Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
Acceso en línea:	https://doaj.org/article/7cd0dd6562bb4abf9d351e865e06a536
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spelling	oai:doaj.org-article:7cd0dd6562bb4abf9d351e865e06a5362021-12-02T17:56:04ZIodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis10.17533/udea.vitae.v28n2a3455720121-40042145-2660https://doaj.org/article/7cd0dd6562bb4abf9d351e865e06a5362021-07-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/345572https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660 Background: Despite current policies of salt iodination, iodine deficiency is still a global public health problem, especially in women. So far, conflicting evidence has been suggested for the prevalence of iodine deficiency in Brazil. Objective: To estimate the prevalence of iodine deficiency and associated factors in women of childbearing age in Brazil. Methods: A systematic review was conducted using databases (PubMed, LILACS, WHO, Scopus, and Capes’ dissertation and thesis), from inception to May 2020. Meta-analyses of proportions were performed using the variance inverse for the fixed model. Reporting and methodological quality were assessed using the Joanna Briggs Institute tool to prevalence studies. Results: Our review identified seven studies published between 2002 e 2017, including 1354 participants, especially pregnant women. All studies presented at least one quality limitation, mainly regarding the sampling method (i.e., convenience) and small sample size. The prevalence of iodine deficiency ranged among studies from 16% to 62%. In contrast, the meta-analysis identified a mean prevalence of 40% (95% confidence interval, CI 37%-43%) for pregnant women and 13% (95% CI 4%-24%) for non-pregnant women. Cumulative meta-analysis suggests a tendency of higher iodine deficiency prevalence from 2018 in pregnant women. Conclusions: Although this systematic review identified studies with poor methodological and reporting quality, a high prevalence of iodine deficiency was identified in pregnant women, reinforcing the importance of national nutritional policies for monitoring iodine status in this population. Future studies should consider random probabilistic sampling, appropriate sample size, and pre-defined subgroup analysis to adequately inform the prevalence of iodine deficiency and associated factors in women of childbearing age and support health policies. Rosa Camila LucchettaAna Luísa Rodriguez GiniSophia de Andrade CavicchioliMarcela ForgeriniFabiana Rossi VaralloMariane Nunes de NadaiFernando Fernandez-LlimósPatricia de Carvalho MastroianniUniversidad de AntioquiaarticleIodine deficiencyPrevalence studyNutritional EpidemiologyMaternal NutritionWomen's HealthFood processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 28, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Iodine deficiency Prevalence study Nutritional Epidemiology Maternal Nutrition Women's Health Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
spellingShingle	Iodine deficiency Prevalence study Nutritional Epidemiology Maternal Nutrition Women's Health Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Rosa Camila Lucchetta Ana Luísa Rodriguez Gini Sophia de Andrade Cavicchioli Marcela Forgerini Fabiana Rossi Varallo Mariane Nunes de Nadai Fernando Fernandez-Llimós Patricia de Carvalho Mastroianni Iodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis
description	Background: Despite current policies of salt iodination, iodine deficiency is still a global public health problem, especially in women. So far, conflicting evidence has been suggested for the prevalence of iodine deficiency in Brazil. Objective: To estimate the prevalence of iodine deficiency and associated factors in women of childbearing age in Brazil. Methods: A systematic review was conducted using databases (PubMed, LILACS, WHO, Scopus, and Capes’ dissertation and thesis), from inception to May 2020. Meta-analyses of proportions were performed using the variance inverse for the fixed model. Reporting and methodological quality were assessed using the Joanna Briggs Institute tool to prevalence studies. Results: Our review identified seven studies published between 2002 e 2017, including 1354 participants, especially pregnant women. All studies presented at least one quality limitation, mainly regarding the sampling method (i.e., convenience) and small sample size. The prevalence of iodine deficiency ranged among studies from 16% to 62%. In contrast, the meta-analysis identified a mean prevalence of 40% (95% confidence interval, CI 37%-43%) for pregnant women and 13% (95% CI 4%-24%) for non-pregnant women. Cumulative meta-analysis suggests a tendency of higher iodine deficiency prevalence from 2018 in pregnant women. Conclusions: Although this systematic review identified studies with poor methodological and reporting quality, a high prevalence of iodine deficiency was identified in pregnant women, reinforcing the importance of national nutritional policies for monitoring iodine status in this population. Future studies should consider random probabilistic sampling, appropriate sample size, and pre-defined subgroup analysis to adequately inform the prevalence of iodine deficiency and associated factors in women of childbearing age and support health policies.
format	article
author	Rosa Camila Lucchetta Ana Luísa Rodriguez Gini Sophia de Andrade Cavicchioli Marcela Forgerini Fabiana Rossi Varallo Mariane Nunes de Nadai Fernando Fernandez-Llimós Patricia de Carvalho Mastroianni
author_facet	Rosa Camila Lucchetta Ana Luísa Rodriguez Gini Sophia de Andrade Cavicchioli Marcela Forgerini Fabiana Rossi Varallo Mariane Nunes de Nadai Fernando Fernandez-Llimós Patricia de Carvalho Mastroianni
author_sort	Rosa Camila Lucchetta
title	Iodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis
title_short	Iodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis
title_full	Iodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis
title_fullStr	Iodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis
title_full_unstemmed	Iodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis
title_sort	iodine deficiency in women of childbearing age in brazil: systematic review and meta-analysis
publisher	Universidad de Antioquia
publishDate	2021
url	https://doaj.org/article/7cd0dd6562bb4abf9d351e865e06a536
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Iodine deficiency in women of childbearing age in Brazil: systematic review and meta-analysis

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