DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death
Chemoresistance is one of the main challenges for cancer therapy success. Here, the authors show that dual-specificity phosphatase 16 (DUSP16) expression is associated with chemoresistance in several types of cancer through impairing mitochondria-associated apoptosis.
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Nature Portfolio
2021
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| Acceso en línea: | https://doaj.org/article/7cd1e1ed821d475f86d18b8927eabe0d |
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oai:doaj.org-article:7cd1e1ed821d475f86d18b8927eabe0d2021-12-02T18:03:13ZDUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death10.1038/s41467-021-22638-72041-1723https://doaj.org/article/7cd1e1ed821d475f86d18b8927eabe0d2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22638-7https://doaj.org/toc/2041-1723Chemoresistance is one of the main challenges for cancer therapy success. Here, the authors show that dual-specificity phosphatase 16 (DUSP16) expression is associated with chemoresistance in several types of cancer through impairing mitochondria-associated apoptosis.Heng Boon LowZhen Lim WongBangyuan WuLi Ren KongChin Wen PngYik-Lam ChoChun-Wei LiFengchun XiaoXuan XinHenry YangJia Min LooFiona Yi Xin LeeIain Bee Huat TanRamanuj DasGuptaHan-Ming ShenHerbert SchwarzNicholas R. J. GascoigneBoon Cher GohXiaohong XuYongliang ZhangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Heng Boon Low Zhen Lim Wong Bangyuan Wu Li Ren Kong Chin Wen Png Yik-Lam Cho Chun-Wei Li Fengchun Xiao Xuan Xin Henry Yang Jia Min Loo Fiona Yi Xin Lee Iain Bee Huat Tan Ramanuj DasGupta Han-Ming Shen Herbert Schwarz Nicholas R. J. Gascoigne Boon Cher Goh Xiaohong Xu Yongliang Zhang DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death |
| description |
Chemoresistance is one of the main challenges for cancer therapy success. Here, the authors show that dual-specificity phosphatase 16 (DUSP16) expression is associated with chemoresistance in several types of cancer through impairing mitochondria-associated apoptosis. |
| format |
article |
| author |
Heng Boon Low Zhen Lim Wong Bangyuan Wu Li Ren Kong Chin Wen Png Yik-Lam Cho Chun-Wei Li Fengchun Xiao Xuan Xin Henry Yang Jia Min Loo Fiona Yi Xin Lee Iain Bee Huat Tan Ramanuj DasGupta Han-Ming Shen Herbert Schwarz Nicholas R. J. Gascoigne Boon Cher Goh Xiaohong Xu Yongliang Zhang |
| author_facet |
Heng Boon Low Zhen Lim Wong Bangyuan Wu Li Ren Kong Chin Wen Png Yik-Lam Cho Chun-Wei Li Fengchun Xiao Xuan Xin Henry Yang Jia Min Loo Fiona Yi Xin Lee Iain Bee Huat Tan Ramanuj DasGupta Han-Ming Shen Herbert Schwarz Nicholas R. J. Gascoigne Boon Cher Goh Xiaohong Xu Yongliang Zhang |
| author_sort |
Heng Boon Low |
| title |
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death |
| title_short |
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death |
| title_full |
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death |
| title_fullStr |
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death |
| title_full_unstemmed |
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death |
| title_sort |
dusp16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/7cd1e1ed821d475f86d18b8927eabe0d |
| work_keys_str_mv |
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| _version_ |
1718378816215187456 |