Cardiac Care of Non-COVID-19 Patients During the SARS-CoV-2 Pandemic: The Pivotal Role of CCTA

Aim: The aim of this study is to evaluate the potential use of coronary CT angiography (CCTA) as the sole available non-invasive diagnostic technique for suspected coronary artery disease (CAD) during the coronavirus disease 2019 (COVID-19) pandemic causing limited access to the hospital facilities....

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Autores principales: Edoardo Conte, Saima Mushtaq, Maria Elisabetta Mancini, Andrea Annoni, Alberto Formenti, Giuseppe Muscogiuri, Margherita Gaudenzi Asinelli, Carlo Gigante, Carlos Collet, Jeroen Sonck, Marco Guglielmo, Andrea Baggiano, Nicola Cosentino, Marialessia Denora, Marta Belmonte, Cecilia Agalbato, Andrea Alessandro Esposito, Emilio Assanelli, Antonio L. Bartorelli, Mauro Pepi, Gianluca Pontone, Daniele Andreini
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/7cd387b3de1f4d81aeff83013f1776ac
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spelling oai:doaj.org-article:7cd387b3de1f4d81aeff83013f1776ac2021-11-30T18:11:56ZCardiac Care of Non-COVID-19 Patients During the SARS-CoV-2 Pandemic: The Pivotal Role of CCTA2297-055X10.3389/fcvm.2021.775115https://doaj.org/article/7cd387b3de1f4d81aeff83013f1776ac2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcvm.2021.775115/fullhttps://doaj.org/toc/2297-055XAim: The aim of this study is to evaluate the potential use of coronary CT angiography (CCTA) as the sole available non-invasive diagnostic technique for suspected coronary artery disease (CAD) during the coronavirus disease 2019 (COVID-19) pandemic causing limited access to the hospital facilities.Methods and Results: A consecutive cohort of patients with suspected stable CAD and clinical indication to non-invasive test was enrolled in a hub hospital in Milan, Italy, from March 9 to April 30, 2020. Outcome measures were obtained as follows: cardiac death, ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina. All the changes in medical therapy following the result of CCTA were annotated. A total of 58 patients with a mean age of 64 ± 11 years (36 men and 22 women) were enrolled. CCTA showed no CAD in 14 patients (24.1%), non-obstructive CAD in 30 (51.7%) patients, and obstructive CAD in 14 (24.1%) patients. Invasive coronary angiography (ICA) was considered deferrable in 48 (82.8%) patients. No clinical events were recorded after a mean follow-up of 376.4 ± 32.1 days. Changes in the medical therapy were significantly more prevalent in patients with vs. those without CAD at CCTA.Conclusion: The results of the study confirm the capability of CCTA to safely defer ICA in the majority of symptomatic patients and to correctly identify those with critical coronary stenoses necessitating coronary revascularization. This characteristic could be really helpful especially when the hospital resources are limitedEdoardo ConteEdoardo ConteSaima MushtaqMaria Elisabetta ManciniAndrea AnnoniAlberto FormentiGiuseppe MuscogiuriMargherita Gaudenzi AsinelliCarlo GiganteCarlos ColletJeroen SonckJeroen SonckMarco GuglielmoAndrea BaggianoNicola CosentinoMarialessia DenoraMarta BelmonteCecilia AgalbatoAndrea Alessandro EspositoEmilio AssanelliAntonio L. BartorelliAntonio L. BartorelliMauro PepiGianluca PontoneDaniele AndreiniDaniele AndreiniFrontiers Media S.A.articleatherosclerosisCOVID-19cardiac CTchest paincoronary artery diseaseDiseases of the circulatory (Cardiovascular) systemRC666-701ENFrontiers in Cardiovascular Medicine, Vol 8 (2021)
institution DOAJ
collection DOAJ
language EN
topic atherosclerosis
COVID-19
cardiac CT
chest pain
coronary artery disease
Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle atherosclerosis
COVID-19
cardiac CT
chest pain
coronary artery disease
Diseases of the circulatory (Cardiovascular) system
RC666-701
Edoardo Conte
Edoardo Conte
Saima Mushtaq
Maria Elisabetta Mancini
Andrea Annoni
Alberto Formenti
Giuseppe Muscogiuri
Margherita Gaudenzi Asinelli
Carlo Gigante
Carlos Collet
Jeroen Sonck
Jeroen Sonck
Marco Guglielmo
Andrea Baggiano
Nicola Cosentino
Marialessia Denora
Marta Belmonte
Cecilia Agalbato
Andrea Alessandro Esposito
Emilio Assanelli
Antonio L. Bartorelli
Antonio L. Bartorelli
Mauro Pepi
Gianluca Pontone
Daniele Andreini
Daniele Andreini
Cardiac Care of Non-COVID-19 Patients During the SARS-CoV-2 Pandemic: The Pivotal Role of CCTA
description Aim: The aim of this study is to evaluate the potential use of coronary CT angiography (CCTA) as the sole available non-invasive diagnostic technique for suspected coronary artery disease (CAD) during the coronavirus disease 2019 (COVID-19) pandemic causing limited access to the hospital facilities.Methods and Results: A consecutive cohort of patients with suspected stable CAD and clinical indication to non-invasive test was enrolled in a hub hospital in Milan, Italy, from March 9 to April 30, 2020. Outcome measures were obtained as follows: cardiac death, ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina. All the changes in medical therapy following the result of CCTA were annotated. A total of 58 patients with a mean age of 64 ± 11 years (36 men and 22 women) were enrolled. CCTA showed no CAD in 14 patients (24.1%), non-obstructive CAD in 30 (51.7%) patients, and obstructive CAD in 14 (24.1%) patients. Invasive coronary angiography (ICA) was considered deferrable in 48 (82.8%) patients. No clinical events were recorded after a mean follow-up of 376.4 ± 32.1 days. Changes in the medical therapy were significantly more prevalent in patients with vs. those without CAD at CCTA.Conclusion: The results of the study confirm the capability of CCTA to safely defer ICA in the majority of symptomatic patients and to correctly identify those with critical coronary stenoses necessitating coronary revascularization. This characteristic could be really helpful especially when the hospital resources are limited
format article
author Edoardo Conte
Edoardo Conte
Saima Mushtaq
Maria Elisabetta Mancini
Andrea Annoni
Alberto Formenti
Giuseppe Muscogiuri
Margherita Gaudenzi Asinelli
Carlo Gigante
Carlos Collet
Jeroen Sonck
Jeroen Sonck
Marco Guglielmo
Andrea Baggiano
Nicola Cosentino
Marialessia Denora
Marta Belmonte
Cecilia Agalbato
Andrea Alessandro Esposito
Emilio Assanelli
Antonio L. Bartorelli
Antonio L. Bartorelli
Mauro Pepi
Gianluca Pontone
Daniele Andreini
Daniele Andreini
author_facet Edoardo Conte
Edoardo Conte
Saima Mushtaq
Maria Elisabetta Mancini
Andrea Annoni
Alberto Formenti
Giuseppe Muscogiuri
Margherita Gaudenzi Asinelli
Carlo Gigante
Carlos Collet
Jeroen Sonck
Jeroen Sonck
Marco Guglielmo
Andrea Baggiano
Nicola Cosentino
Marialessia Denora
Marta Belmonte
Cecilia Agalbato
Andrea Alessandro Esposito
Emilio Assanelli
Antonio L. Bartorelli
Antonio L. Bartorelli
Mauro Pepi
Gianluca Pontone
Daniele Andreini
Daniele Andreini
author_sort Edoardo Conte
title Cardiac Care of Non-COVID-19 Patients During the SARS-CoV-2 Pandemic: The Pivotal Role of CCTA
title_short Cardiac Care of Non-COVID-19 Patients During the SARS-CoV-2 Pandemic: The Pivotal Role of CCTA
title_full Cardiac Care of Non-COVID-19 Patients During the SARS-CoV-2 Pandemic: The Pivotal Role of CCTA
title_fullStr Cardiac Care of Non-COVID-19 Patients During the SARS-CoV-2 Pandemic: The Pivotal Role of CCTA
title_full_unstemmed Cardiac Care of Non-COVID-19 Patients During the SARS-CoV-2 Pandemic: The Pivotal Role of CCTA
title_sort cardiac care of non-covid-19 patients during the sars-cov-2 pandemic: the pivotal role of ccta
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/7cd387b3de1f4d81aeff83013f1776ac
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