In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.

Mitogen activated protein kinase kinase kinase (MAPKKK) form the upstream component of MAPK cascade. It is well characterized in several plants such as Arabidopsis and rice however the knowledge about MAPKKKs in tea plant is largely unknown. In the present study, MAPKKK genes of tea were obtained th...

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Autores principales:	Abhirup Paul, Anurag P Srivastava, Shreya Subrahmanya, Guoxin Shen, Neelam Mishra
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7cd8d87003894c4a9ffd548a159469bd
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spelling	oai:doaj.org-article:7cd8d87003894c4a9ffd548a159469bd2021-12-02T20:04:23ZIn-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.1932-620310.1371/journal.pone.0258657https://doaj.org/article/7cd8d87003894c4a9ffd548a159469bd2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0258657https://doaj.org/toc/1932-6203Mitogen activated protein kinase kinase kinase (MAPKKK) form the upstream component of MAPK cascade. It is well characterized in several plants such as Arabidopsis and rice however the knowledge about MAPKKKs in tea plant is largely unknown. In the present study, MAPKKK genes of tea were obtained through a genome wide search using Arabidopsis thaliana as the reference genome. Among 59 candidate MAPKKK genes in tea, 17 genes were MEKK-like, 31 genes were Raf-like and 11 genes were ZIK- like. Additionally, phylogenetic relationships were established along with structural analysis, which includes gene structure, its location as well as conserved motifs, cis-acting regulatory elements and functional domain signatures that were systematically examined. Also, on the basis of one orthologous gene found between tea and Arabidopsis, functional interaction was carried out in C. sinensis based on an Arabidopsis association model. The expressional profiles indicated major involvement of MAPKKK genes from tea in response to various abiotic stress factors. Taken together, this study provides the targets for additional inclusive identification, functional study, and provides comprehensive knowledge for a better understanding of the MAPKKK cascade regulatory network in C. sinensis.Abhirup PaulAnurag P SrivastavaShreya SubrahmanyaGuoxin ShenNeelam MishraPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11, p e0258657 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Abhirup Paul Anurag P Srivastava Shreya Subrahmanya Guoxin Shen Neelam Mishra In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.
description	Mitogen activated protein kinase kinase kinase (MAPKKK) form the upstream component of MAPK cascade. It is well characterized in several plants such as Arabidopsis and rice however the knowledge about MAPKKKs in tea plant is largely unknown. In the present study, MAPKKK genes of tea were obtained through a genome wide search using Arabidopsis thaliana as the reference genome. Among 59 candidate MAPKKK genes in tea, 17 genes were MEKK-like, 31 genes were Raf-like and 11 genes were ZIK- like. Additionally, phylogenetic relationships were established along with structural analysis, which includes gene structure, its location as well as conserved motifs, cis-acting regulatory elements and functional domain signatures that were systematically examined. Also, on the basis of one orthologous gene found between tea and Arabidopsis, functional interaction was carried out in C. sinensis based on an Arabidopsis association model. The expressional profiles indicated major involvement of MAPKKK genes from tea in response to various abiotic stress factors. Taken together, this study provides the targets for additional inclusive identification, functional study, and provides comprehensive knowledge for a better understanding of the MAPKKK cascade regulatory network in C. sinensis.
format	article
author	Abhirup Paul Anurag P Srivastava Shreya Subrahmanya Guoxin Shen Neelam Mishra
author_facet	Abhirup Paul Anurag P Srivastava Shreya Subrahmanya Guoxin Shen Neelam Mishra
author_sort	Abhirup Paul
title	In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.
title_short	In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.
title_full	In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.
title_fullStr	In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.
title_full_unstemmed	In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.
title_sort	in-silico genome wide analysis of mitogen activated protein kinase kinase kinase gene family in c. sinensis.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/7cd8d87003894c4a9ffd548a159469bd
work_keys_str_mv	AT abhiruppaul insilicogenomewideanalysisofmitogenactivatedproteinkinasekinasekinasegenefamilyincsinensis AT anuragpsrivastava insilicogenomewideanalysisofmitogenactivatedproteinkinasekinasekinasegenefamilyincsinensis AT shreyasubrahmanya insilicogenomewideanalysisofmitogenactivatedproteinkinasekinasekinasegenefamilyincsinensis AT guoxinshen insilicogenomewideanalysisofmitogenactivatedproteinkinasekinasekinasegenefamilyincsinensis AT neelammishra insilicogenomewideanalysisofmitogenactivatedproteinkinasekinasekinasegenefamilyincsinensis
_version_	1718375611521564672

In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.

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