Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3

Conjugative transfer of antibiotic resistance plasmid pCW3 in Clostridium perfringens is mediated by the tcp locus. Here, the authors identify a wHTH-type protein, TcpK, that is essential for efficient plasmid transfer and interacts with the plasmid oriT region in a unique manner.

Guardado en:

Detalles Bibliográficos
Autores principales:	Daouda A. K. Traore, Jessica A. Wisniewski, Sarena F. Flanigan, Paul J. Conroy, Santosh Panjikar, Yee-Foong Mok, Carmen Lao, Michael D. W. Griffin, Vicki Adams, Julian I. Rood, James C. Whisstock
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7cda5168800047dcbc57499355c58da2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7cda5168800047dcbc57499355c58da2
record_format	dspace
spelling	oai:doaj.org-article:7cda5168800047dcbc57499355c58da22021-12-02T17:31:45ZCrystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW310.1038/s41467-018-06096-22041-1723https://doaj.org/article/7cda5168800047dcbc57499355c58da22018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06096-2https://doaj.org/toc/2041-1723Conjugative transfer of antibiotic resistance plasmid pCW3 in Clostridium perfringens is mediated by the tcp locus. Here, the authors identify a wHTH-type protein, TcpK, that is essential for efficient plasmid transfer and interacts with the plasmid oriT region in a unique manner.Daouda A. K. TraoreJessica A. WisniewskiSarena F. FlaniganPaul J. ConroySantosh PanjikarYee-Foong MokCarmen LaoMichael D. W. GriffinVicki AdamsJulian I. RoodJames C. WhisstockNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daouda A. K. Traore Jessica A. Wisniewski Sarena F. Flanigan Paul J. Conroy Santosh Panjikar Yee-Foong Mok Carmen Lao Michael D. W. Griffin Vicki Adams Julian I. Rood James C. Whisstock Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
description	Conjugative transfer of antibiotic resistance plasmid pCW3 in Clostridium perfringens is mediated by the tcp locus. Here, the authors identify a wHTH-type protein, TcpK, that is essential for efficient plasmid transfer and interacts with the plasmid oriT region in a unique manner.
format	article
author	Daouda A. K. Traore Jessica A. Wisniewski Sarena F. Flanigan Paul J. Conroy Santosh Panjikar Yee-Foong Mok Carmen Lao Michael D. W. Griffin Vicki Adams Julian I. Rood James C. Whisstock
author_facet	Daouda A. K. Traore Jessica A. Wisniewski Sarena F. Flanigan Paul J. Conroy Santosh Panjikar Yee-Foong Mok Carmen Lao Michael D. W. Griffin Vicki Adams Julian I. Rood James C. Whisstock
author_sort	Daouda A. K. Traore
title	Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
title_short	Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
title_full	Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
title_fullStr	Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
title_full_unstemmed	Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
title_sort	crystal structure of tcpk in complex with orit dna of the antibiotic resistance plasmid pcw3
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7cda5168800047dcbc57499355c58da2
work_keys_str_mv	AT daoudaaktraore crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT jessicaawisniewski crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT sarenafflanigan crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT pauljconroy crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT santoshpanjikar crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT yeefoongmok crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT carmenlao crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT michaeldwgriffin crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT vickiadams crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT julianirood crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3 AT jamescwhisstock crystalstructureoftcpkincomplexwithoritdnaoftheantibioticresistanceplasmidpcw3
_version_	1718380500486193152

Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3

Ejemplares similares