Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules

Yan-Xia Zhang, Ji-Ping Xue, Hui-Zhan Li, Jun-Wang Miao, Chun-Song Kang Department of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, 030032, People’s Republic of ChinaCorrespondence: Chun-Song KangDepartment of Ultra...

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Autores principales:	Zhang YX, Xue JP, Li HZ, Miao JW, Kang CS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	thyroid nodules ultrasound shear wave elastography color characteristic Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/7cdab776aa794fd289e512a36ffdd2d5
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spelling	oai:doaj.org-article:7cdab776aa794fd289e512a36ffdd2d52021-11-09T18:40:34ZClinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules1178-7074https://doaj.org/article/7cdab776aa794fd289e512a36ffdd2d52021-11-01T00:00:00Zhttps://www.dovepress.com/clinical-value-of-shear-wave-elastography-color-scores-in-classifying--peer-reviewed-fulltext-article-IJGMhttps://doaj.org/toc/1178-7074Yan-Xia Zhang, Ji-Ping Xue, Hui-Zhan Li, Jun-Wang Miao, Chun-Song Kang Department of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, 030032, People’s Republic of ChinaCorrespondence: Chun-Song KangDepartment of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, 030032, People’s Republic of ChinaTel +86-13834518776Email kcsdr_09sea@163.comObjective: To evaluate the clinical value of qualitative shear wave elastography (SWE) color in the differential diagnosis of benign and malignant thyroid nodules.Methods: From January 2017 to July 2018, 241 patients with 261 thyroid nodules, who underwent conventional ultrasonography and SWE examination before surgical resection, were enrolled. The nodules were also evaluated by histopathologic analyses. The SWE color characteristics that could differentiate malignant and benign thyroid nodules were selected and scored based on the malignancy rate. The diagnostic performances were evaluated by receiver operating characteristic (ROC) curves analysis.Results: Among the 261 thyroid nodules, 58 were benign, and 203 were malignant. Malignancy was associated with orange or red as the color of maximum hardness inside a nodule, green as the primary color, with a “stiff rim,” inhomogeneous internal color, and inhomogeneous color between the nodules and its surrounding areas. The SWE color scores for benign thyroid nodules were mainly 0 and 1, while 4 and 5 were for malignant thyroid nodules. The area under the ROC curve (AUC) of the SWE color score ≥ 3 for the diagnosis of malignant thyroid nodules was 0.828 (95% CI: 0.764, 0.891) with a sensitivity of 82.8%, a specificity of 82.8%, and an accuracy of 83.1%. Additionally, conventional ultrasound combined with SWE color scores had a higher diagnostic performance than conventional ultrasound (AUC 0.820 vs AUC 0.796, P = 0.04).Conclusion: The SWE color scores might be a convenient and effective method to assist in differentiating thyroid nodules.Keywords: thyroid nodules, ultrasound, shear wave elastography, color characteristicZhang YXXue JPLi HZMiao JWKang CSDove Medical Pressarticlethyroid nodulesultrasoundshear wave elastographycolor characteristicMedicine (General)R5-920ENInternational Journal of General Medicine, Vol Volume 14, Pp 8007-8018 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	thyroid nodules ultrasound shear wave elastography color characteristic Medicine (General) R5-920
spellingShingle	thyroid nodules ultrasound shear wave elastography color characteristic Medicine (General) R5-920 Zhang YX Xue JP Li HZ Miao JW Kang CS Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules
description	Yan-Xia Zhang, Ji-Ping Xue, Hui-Zhan Li, Jun-Wang Miao, Chun-Song Kang Department of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, 030032, People’s Republic of ChinaCorrespondence: Chun-Song KangDepartment of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, 030032, People’s Republic of ChinaTel +86-13834518776Email kcsdr_09sea@163.comObjective: To evaluate the clinical value of qualitative shear wave elastography (SWE) color in the differential diagnosis of benign and malignant thyroid nodules.Methods: From January 2017 to July 2018, 241 patients with 261 thyroid nodules, who underwent conventional ultrasonography and SWE examination before surgical resection, were enrolled. The nodules were also evaluated by histopathologic analyses. The SWE color characteristics that could differentiate malignant and benign thyroid nodules were selected and scored based on the malignancy rate. The diagnostic performances were evaluated by receiver operating characteristic (ROC) curves analysis.Results: Among the 261 thyroid nodules, 58 were benign, and 203 were malignant. Malignancy was associated with orange or red as the color of maximum hardness inside a nodule, green as the primary color, with a “stiff rim,” inhomogeneous internal color, and inhomogeneous color between the nodules and its surrounding areas. The SWE color scores for benign thyroid nodules were mainly 0 and 1, while 4 and 5 were for malignant thyroid nodules. The area under the ROC curve (AUC) of the SWE color score ≥ 3 for the diagnosis of malignant thyroid nodules was 0.828 (95% CI: 0.764, 0.891) with a sensitivity of 82.8%, a specificity of 82.8%, and an accuracy of 83.1%. Additionally, conventional ultrasound combined with SWE color scores had a higher diagnostic performance than conventional ultrasound (AUC 0.820 vs AUC 0.796, P = 0.04).Conclusion: The SWE color scores might be a convenient and effective method to assist in differentiating thyroid nodules.Keywords: thyroid nodules, ultrasound, shear wave elastography, color characteristic
format	article
author	Zhang YX Xue JP Li HZ Miao JW Kang CS
author_facet	Zhang YX Xue JP Li HZ Miao JW Kang CS
author_sort	Zhang YX
title	Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules
title_short	Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules
title_full	Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules
title_fullStr	Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules
title_full_unstemmed	Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules
title_sort	clinical value of shear wave elastography color scores in classifying thyroid nodules
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/7cdab776aa794fd289e512a36ffdd2d5
work_keys_str_mv	AT zhangyx clinicalvalueofshearwaveelastographycolorscoresinclassifyingthyroidnodules AT xuejp clinicalvalueofshearwaveelastographycolorscoresinclassifyingthyroidnodules AT lihz clinicalvalueofshearwaveelastographycolorscoresinclassifyingthyroidnodules AT miaojw clinicalvalueofshearwaveelastographycolorscoresinclassifyingthyroidnodules AT kangcs clinicalvalueofshearwaveelastographycolorscoresinclassifyingthyroidnodules
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Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules

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