Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.

Annual influenza epidemics and occasional pandemics pose a severe threat to human health. Host cell factors required for viral spread but not for cellular survival are attractive targets for novel approaches to antiviral intervention. The cleavage activation of the influenza virus hemagglutinin (HA)...

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Autores principales: Bastian Hatesuer, Stephanie Bertram, Nora Mehnert, Mahmoud M Bahgat, Peter S Nelson, Stefan Pöhlmann, Klaus Schughart
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/7cdc567aa0b24c34ae5832e23347ce0d
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