Rational design of a new Trypanosoma rangeli trans-sialidase for efficient sialylation of glycans.
This paper reports rational engineering of Trypanosoma rangeli sialidase to develop an effective enzyme for a potentially important type of reactivity: production of sialylated prebiotic glycans. The Trypanosoma cruzi trans-sialidase and the homologous T. rangeli sialidase has previously been used t...
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Main Authors: | Carsten Jers, Malwina Michalak, Dorte M Larsen, Kasper P Kepp, Haiying Li, Yao Guo, Finn Kirpekar, Anne S Meyer, Jørn D Mikkelsen |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Subjects: | |
Online Access: | https://doaj.org/article/7ce5c01b05ce4c2b82b60c94e2281430 |
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