Promiscuous and Adaptable Enzymes Fill “Holes” in the Tetrahydrofolate Pathway in <italic toggle="yes">Chlamydia</italic> Species

ABSTRACT Folates are tripartite molecules comprising pterin, para-aminobenzoate (PABA), and glutamate moieties, which are essential cofactors involved in DNA and amino acid synthesis. The obligately intracellular Chlamydia species have lost several biosynthetic pathways for essential nutrients which...

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Main Authors: Nancy E. Adams, Jennifer J. Thiaville, James Proestos, Ana L. Juárez-Vázquez, Andrea J. McCoy, Francisco Barona-Gómez, Dirk Iwata-Reuyl, Valérie de Crécy-Lagard, Anthony T. Maurelli
Format: article
Language:EN
Published: American Society for Microbiology 2014
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Online Access:https://doaj.org/article/7cea6c28e1c54e0aaa048267f8376ef9
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