Spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons

Abstract The spatial location and viewpoint of observed actions are closely linked in natural social settings. For example, actions observed from a subjective viewpoint necessarily occur within the observer’s peripersonal space. Neurophysiological studies have shown that mirror neurons (MNs) of the...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Monica Maranesi, Alessandro Livi, Luca Bonini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7cea9a287a0b450399ef43368c42282b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7cea9a287a0b450399ef43368c42282b
record_format	dspace
spelling	oai:doaj.org-article:7cea9a287a0b450399ef43368c42282b2021-12-02T12:32:52ZSpatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons10.1038/s41598-017-08956-12045-2322https://doaj.org/article/7cea9a287a0b450399ef43368c42282b2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08956-1https://doaj.org/toc/2045-2322Abstract The spatial location and viewpoint of observed actions are closely linked in natural social settings. For example, actions observed from a subjective viewpoint necessarily occur within the observer’s peripersonal space. Neurophysiological studies have shown that mirror neurons (MNs) of the monkey ventral premotor area F5 can code the spatial location of live observed actions. Furthermore, F5 MN discharge can also be modulated by the viewpoint from which filmed actions are seen. Nonetheless, whether and to what extent MNs can integrate viewpoint and spatial location of live observed actions remains unknown. We addressed this issue by comparing the activity of 148 F5 MNs while macaque monkeys observed an experimenter grasping in three different combinations of viewpoint and spatial location, namely, lateral view in the (1) extrapersonal and (2) peripersonal space and (3) subjective view in the peripersonal space. We found that the majority of MNs were space-selective (60.8%): those selective for the peripersonal space exhibited a preference for the subjective viewpoint both at the single-neuron and population level, whereas space-unselective neurons were view invariant. These findings reveal the existence of a previously neglected link between spatial and viewpoint selectivity in MN activity during live-action observation.Monica MaranesiAlessandro LiviLuca BoniniNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Monica Maranesi Alessandro Livi Luca Bonini Spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons
description	Abstract The spatial location and viewpoint of observed actions are closely linked in natural social settings. For example, actions observed from a subjective viewpoint necessarily occur within the observer’s peripersonal space. Neurophysiological studies have shown that mirror neurons (MNs) of the monkey ventral premotor area F5 can code the spatial location of live observed actions. Furthermore, F5 MN discharge can also be modulated by the viewpoint from which filmed actions are seen. Nonetheless, whether and to what extent MNs can integrate viewpoint and spatial location of live observed actions remains unknown. We addressed this issue by comparing the activity of 148 F5 MNs while macaque monkeys observed an experimenter grasping in three different combinations of viewpoint and spatial location, namely, lateral view in the (1) extrapersonal and (2) peripersonal space and (3) subjective view in the peripersonal space. We found that the majority of MNs were space-selective (60.8%): those selective for the peripersonal space exhibited a preference for the subjective viewpoint both at the single-neuron and population level, whereas space-unselective neurons were view invariant. These findings reveal the existence of a previously neglected link between spatial and viewpoint selectivity in MN activity during live-action observation.
format	article
author	Monica Maranesi Alessandro Livi Luca Bonini
author_facet	Monica Maranesi Alessandro Livi Luca Bonini
author_sort	Monica Maranesi
title	Spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons
title_short	Spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons
title_full	Spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons
title_fullStr	Spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons
title_full_unstemmed	Spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons
title_sort	spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7cea9a287a0b450399ef43368c42282b
work_keys_str_mv	AT monicamaranesi spatialandviewpointselectivityforothersobservedactionsinmonkeyventralpremotormirrorneurons AT alessandrolivi spatialandviewpointselectivityforothersobservedactionsinmonkeyventralpremotormirrorneurons AT lucabonini spatialandviewpointselectivityforothersobservedactionsinmonkeyventralpremotormirrorneurons
_version_	1718393927781842944

Spatial and viewpoint selectivity for others’ observed actions in monkey ventral premotor mirror neurons

Ejemplares similares