Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia

Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with de...

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Autores principales: Carmen Gasca-Salas, Beatriz Fernández-Rodríguez, José A. Pineda-Pardo, Rafael Rodríguez-Rojas, Ignacio Obeso, Frida Hernández-Fernández, Marta del Álamo, David Mata, Pasqualina Guida, Carlos Ordás-Bandera, J. Ignacio Montero-Roblas, Raúl Martínez-Fernández, Guglielmo Foffani, Itay Rachmilevitch, José A. Obeso
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7cf8f633f4864b079a9626f71c959e9a
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Sumario:Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with dementia.