Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia

Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with de...

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Autores principales: Carmen Gasca-Salas, Beatriz Fernández-Rodríguez, José A. Pineda-Pardo, Rafael Rodríguez-Rojas, Ignacio Obeso, Frida Hernández-Fernández, Marta del Álamo, David Mata, Pasqualina Guida, Carlos Ordás-Bandera, J. Ignacio Montero-Roblas, Raúl Martínez-Fernández, Guglielmo Foffani, Itay Rachmilevitch, José A. Obeso
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7cf8f633f4864b079a9626f71c959e9a
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spelling oai:doaj.org-article:7cf8f633f4864b079a9626f71c959e9a2021-12-02T14:33:40ZBlood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia10.1038/s41467-021-21022-92041-1723https://doaj.org/article/7cf8f633f4864b079a9626f71c959e9a2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21022-9https://doaj.org/toc/2041-1723Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with dementia.Carmen Gasca-SalasBeatriz Fernández-RodríguezJosé A. Pineda-PardoRafael Rodríguez-RojasIgnacio ObesoFrida Hernández-FernándezMarta del ÁlamoDavid MataPasqualina GuidaCarlos Ordás-BanderaJ. Ignacio Montero-RoblasRaúl Martínez-FernándezGuglielmo FoffaniItay RachmilevitchJosé A. ObesoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Carmen Gasca-Salas
Beatriz Fernández-Rodríguez
José A. Pineda-Pardo
Rafael Rodríguez-Rojas
Ignacio Obeso
Frida Hernández-Fernández
Marta del Álamo
David Mata
Pasqualina Guida
Carlos Ordás-Bandera
J. Ignacio Montero-Roblas
Raúl Martínez-Fernández
Guglielmo Foffani
Itay Rachmilevitch
José A. Obeso
Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
description Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with dementia.
format article
author Carmen Gasca-Salas
Beatriz Fernández-Rodríguez
José A. Pineda-Pardo
Rafael Rodríguez-Rojas
Ignacio Obeso
Frida Hernández-Fernández
Marta del Álamo
David Mata
Pasqualina Guida
Carlos Ordás-Bandera
J. Ignacio Montero-Roblas
Raúl Martínez-Fernández
Guglielmo Foffani
Itay Rachmilevitch
José A. Obeso
author_facet Carmen Gasca-Salas
Beatriz Fernández-Rodríguez
José A. Pineda-Pardo
Rafael Rodríguez-Rojas
Ignacio Obeso
Frida Hernández-Fernández
Marta del Álamo
David Mata
Pasqualina Guida
Carlos Ordás-Bandera
J. Ignacio Montero-Roblas
Raúl Martínez-Fernández
Guglielmo Foffani
Itay Rachmilevitch
José A. Obeso
author_sort Carmen Gasca-Salas
title Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
title_short Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
title_full Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
title_fullStr Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
title_full_unstemmed Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
title_sort blood-brain barrier opening with focused ultrasound in parkinson’s disease dementia
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7cf8f633f4864b079a9626f71c959e9a
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