IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER

In patients with diffuse toxic goiter (DTG), relative numbers of CD4+, CD8+ lymphocytes, activated T-lymphocytes (CD3+HLA-DR+) proved to be increased, whereas absolute contents of T-independent (CD3-CD16+CD56+), and T-dependent (CD3+CD16+CD56+) NK-cells were found to be decreased. Moreover, IgA and...

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Autores principales:	B. I. Kuznik, Yu. A. Vitkovsky, O. V. Gvozdeva, O. S. Rodnina, A. V. Solpov
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	goiter immunity leukocyte/rbc/platelet agregates Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/7d0322a91ff04e1198b931c0dea17017
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spelling	oai:doaj.org-article:7d0322a91ff04e1198b931c0dea170172021-11-18T08:03:37ZIMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER1563-06252313-741X10.15789/1563-0625-2010-1-2-133-138https://doaj.org/article/7d0322a91ff04e1198b931c0dea170172014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/56https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XIn patients with diffuse toxic goiter (DTG), relative numbers of CD4+, CD8+ lymphocytes, activated T-lymphocytes (CD3+HLA-DR+) proved to be increased, whereas absolute contents of T-independent (CD3-CD16+CD56+), and T-dependent (CD3+CD16+CD56+) NK-cells were found to be decreased. Moreover, IgA and IgM levels were decreased among DTG patients. In most DTG cases, amounts of lymphocyte-to-platelet agregates were sharply decreased. Studying parameters of immunogram, lymphocyte-platelet adhesion allows of assessing specific changes of adaptive immune response in diffuse toxic goiter.B. I. KuznikYu. A. VitkovskyO. V. GvozdevaO. S. RodninaA. V. SolpovSPb RAACIarticlegoiterimmunityleukocyte/rbc/platelet agregatesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 1-2, Pp 133-138 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	goiter immunity leukocyte/rbc/platelet agregates Immunologic diseases. Allergy RC581-607
spellingShingle	goiter immunity leukocyte/rbc/platelet agregates Immunologic diseases. Allergy RC581-607 B. I. Kuznik Yu. A. Vitkovsky O. V. Gvozdeva O. S. Rodnina A. V. Solpov IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER
description	In patients with diffuse toxic goiter (DTG), relative numbers of CD4+, CD8+ lymphocytes, activated T-lymphocytes (CD3+HLA-DR+) proved to be increased, whereas absolute contents of T-independent (CD3-CD16+CD56+), and T-dependent (CD3+CD16+CD56+) NK-cells were found to be decreased. Moreover, IgA and IgM levels were decreased among DTG patients. In most DTG cases, amounts of lymphocyte-to-platelet agregates were sharply decreased. Studying parameters of immunogram, lymphocyte-platelet adhesion allows of assessing specific changes of adaptive immune response in diffuse toxic goiter.
format	article
author	B. I. Kuznik Yu. A. Vitkovsky O. V. Gvozdeva O. S. Rodnina A. V. Solpov
author_facet	B. I. Kuznik Yu. A. Vitkovsky O. V. Gvozdeva O. S. Rodnina A. V. Solpov
author_sort	B. I. Kuznik
title	IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER
title_short	IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER
title_full	IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER
title_fullStr	IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER
title_full_unstemmed	IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER
title_sort	immunity and lymphocyte-platelet adhesion in diffuse toxic goiter
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/7d0322a91ff04e1198b931c0dea17017
work_keys_str_mv	AT bikuznik immunityandlymphocyteplateletadhesionindiffusetoxicgoiter AT yuavitkovsky immunityandlymphocyteplateletadhesionindiffusetoxicgoiter AT ovgvozdeva immunityandlymphocyteplateletadhesionindiffusetoxicgoiter AT osrodnina immunityandlymphocyteplateletadhesionindiffusetoxicgoiter AT avsolpov immunityandlymphocyteplateletadhesionindiffusetoxicgoiter
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IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN DIFFUSE TOXIC GOITER

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