<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics

ABSTRACT Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bac...

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Autores principales: Han Zhao, Shaliu Fu, Yifei Yu, Zhanbing Zhang, Ping Li, Qin Ma, Wei Jia, Kang Ning, Shen Qu, Qi Liu
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/7d142ef2bb4145d8833d7f7a4126decb
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spelling oai:doaj.org-article:7d142ef2bb4145d8833d7f7a4126decb2021-12-02T19:46:17Z<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics10.1128/mSystems.00413-192379-5077https://doaj.org/article/7d142ef2bb4145d8833d7f7a4126decb2019-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00413-19https://doaj.org/toc/2379-5077ABSTRACT Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bacterial functions and medicine therapeutics, providing novel hypotheses for deep investigation of microbe therapeutic effects on human health. Furthermore, comprehensive relationships between microbes living in the environment and drugs were discovered, providing a rich source for discovering microbiota metabolites with great potential for pharmaceutical applications.Han ZhaoShaliu FuYifei YuZhanbing ZhangPing LiQin MaWei JiaKang NingShen QuQi LiuAmerican Society for Microbiologyarticlemicrobiotametabolismbiosynthetic gene clustersmedicine therapeuticsMicrobiologyQR1-502ENmSystems, Vol 4, Iss 5 (2019)
institution DOAJ
collection DOAJ
language EN
topic microbiota
metabolism
biosynthetic gene clusters
medicine therapeutics
Microbiology
QR1-502
spellingShingle microbiota
metabolism
biosynthetic gene clusters
medicine therapeutics
Microbiology
QR1-502
Han Zhao
Shaliu Fu
Yifei Yu
Zhanbing Zhang
Ping Li
Qin Ma
Wei Jia
Kang Ning
Shen Qu
Qi Liu
<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics
description ABSTRACT Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bacterial functions and medicine therapeutics, providing novel hypotheses for deep investigation of microbe therapeutic effects on human health. Furthermore, comprehensive relationships between microbes living in the environment and drugs were discovered, providing a rich source for discovering microbiota metabolites with great potential for pharmaceutical applications.
format article
author Han Zhao
Shaliu Fu
Yifei Yu
Zhanbing Zhang
Ping Li
Qin Ma
Wei Jia
Kang Ning
Shen Qu
Qi Liu
author_facet Han Zhao
Shaliu Fu
Yifei Yu
Zhanbing Zhang
Ping Li
Qin Ma
Wei Jia
Kang Ning
Shen Qu
Qi Liu
author_sort Han Zhao
title <italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics
title_short <italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics
title_full <italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics
title_fullStr <italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics
title_full_unstemmed <italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics
title_sort <italic toggle="yes">metamed</italic>: linking microbiota functions with medicine therapeutics
publisher American Society for Microbiology
publishDate 2019
url https://doaj.org/article/7d142ef2bb4145d8833d7f7a4126decb
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