<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics
ABSTRACT Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bac...
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American Society for Microbiology
2019
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oai:doaj.org-article:7d142ef2bb4145d8833d7f7a4126decb2021-12-02T19:46:17Z<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics10.1128/mSystems.00413-192379-5077https://doaj.org/article/7d142ef2bb4145d8833d7f7a4126decb2019-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00413-19https://doaj.org/toc/2379-5077ABSTRACT Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bacterial functions and medicine therapeutics, providing novel hypotheses for deep investigation of microbe therapeutic effects on human health. Furthermore, comprehensive relationships between microbes living in the environment and drugs were discovered, providing a rich source for discovering microbiota metabolites with great potential for pharmaceutical applications.Han ZhaoShaliu FuYifei YuZhanbing ZhangPing LiQin MaWei JiaKang NingShen QuQi LiuAmerican Society for Microbiologyarticlemicrobiotametabolismbiosynthetic gene clustersmedicine therapeuticsMicrobiologyQR1-502ENmSystems, Vol 4, Iss 5 (2019) |
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microbiota metabolism biosynthetic gene clusters medicine therapeutics Microbiology QR1-502 |
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microbiota metabolism biosynthetic gene clusters medicine therapeutics Microbiology QR1-502 Han Zhao Shaliu Fu Yifei Yu Zhanbing Zhang Ping Li Qin Ma Wei Jia Kang Ning Shen Qu Qi Liu <italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics |
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ABSTRACT Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bacterial functions and medicine therapeutics, providing novel hypotheses for deep investigation of microbe therapeutic effects on human health. Furthermore, comprehensive relationships between microbes living in the environment and drugs were discovered, providing a rich source for discovering microbiota metabolites with great potential for pharmaceutical applications. |
format |
article |
author |
Han Zhao Shaliu Fu Yifei Yu Zhanbing Zhang Ping Li Qin Ma Wei Jia Kang Ning Shen Qu Qi Liu |
author_facet |
Han Zhao Shaliu Fu Yifei Yu Zhanbing Zhang Ping Li Qin Ma Wei Jia Kang Ning Shen Qu Qi Liu |
author_sort |
Han Zhao |
title |
<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics |
title_short |
<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics |
title_full |
<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics |
title_fullStr |
<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics |
title_full_unstemmed |
<italic toggle="yes">MetaMed</italic>: Linking Microbiota Functions with Medicine Therapeutics |
title_sort |
<italic toggle="yes">metamed</italic>: linking microbiota functions with medicine therapeutics |
publisher |
American Society for Microbiology |
publishDate |
2019 |
url |
https://doaj.org/article/7d142ef2bb4145d8833d7f7a4126decb |
work_keys_str_mv |
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1718376034660777984 |