Identification of an Immunogenic Broadly Inhibitory Surface Epitope of the <named-content content-type="genus-species">Plasmodium vivax</named-content> Duffy Binding Protein Ligand Domain

Identification of an Immunogenic Broadly Inhibitory Surface Epitope of the <named-content content-type="genus-species">Plasmodium vivax</named-content> Duffy Binding Protein Ligand Domain

ABSTRACT The Plasmodium vivax Duffy binding protein region II (DBPII) is a vital ligand for the parasite’s invasion of reticulocytes, thereby making this molecule an attractive vaccine candidate against vivax malaria. However, strain-specific immunity due to DBPII allelic variation in Bc epitopes ma...

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Autores principales: Miriam T. George, Jesse L. Schloegel, Francis B. Ntumngia, Samantha J. Barnes, Christopher L. King, Joanne L. Casey, Michael Foley, John H. Adams
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
DBPII
Plasmodium vivax
epitope mapping
malaria
vaccine
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/7d160bd61e2246ffac628b8c97927e47
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