The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABAA receptors

The netrin receptor UNC-40/DCC is required to recruit GABAAR at neuromuscular junctions in C. elegans. Here, the authors show that UNC-40/DCC assembles an intracellular synaptic scaffold, regulating the content of GABAAR and inhibitory neurotransmission.

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Autores principales: Xin Zhou, Marine Gueydan, Maelle Jospin, Tingting Ji, Aurore Valfort, Bérangère Pinan-Lucarré, Jean-Louis Bessereau
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/7d1978beeef44807a09ef637fddb90d3
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