Aspirin and Sulindac act via different mechanisms to inhibit store-operated calcium channel: Implications for colorectal cancer metastasis

Store-operated Ca2+ channel (SOC)-regulated Ca2+ entry is involved in inflammation and colorectal cancer (CRC) progression, but clinically applicable treatments targeting this mechanism are lacking. Recent studies have shown that nonsteroidal anti-inflammatory drugs (NSAIDs) not only inhibit inflamm...

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Bibliographic Details
Main Authors: Yu-Shiuan Wang, Nai-Kuei Huang, Yu-Chiao Lin, Wei-Chiao Chang, Wan-Chen Huang
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
SOC
Online Access:https://doaj.org/article/7d2115d68a7c43f58e0b8f5a8e3c4e8e
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