Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

Plasmodium protein phosphatase PP1 is essential for the asexual proliferation of malaria parasites. Here the authors show that PP1 regulates egress of parasites from host red blood cells, integrating parasite intrinsic pathways with environmental signals for release into the bloodstream.

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Autores principales:	Aditya S. Paul, Alexandra Miliu, Joao A. Paulo, Jonathan M. Goldberg, Arianna M. Bonilla, Laurence Berry, Marie Seveno, Catherine Braun-Breton, Aziz L. Kosber, Brendan Elsworth, Jose S. N. Arriola, Maryse Lebrun, Steven P. Gygi, Mauld H. Lamarque, Manoj T. Duraisingh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7d2715bdc7484f8c88c035dcb70a2f3f
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spelling	oai:doaj.org-article:7d2715bdc7484f8c88c035dcb70a2f3f2021-12-02T17:01:29ZCo-option of Plasmodium falciparum PP1 for egress from host erythrocytes10.1038/s41467-020-17306-12041-1723https://doaj.org/article/7d2715bdc7484f8c88c035dcb70a2f3f2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17306-1https://doaj.org/toc/2041-1723Plasmodium protein phosphatase PP1 is essential for the asexual proliferation of malaria parasites. Here the authors show that PP1 regulates egress of parasites from host red blood cells, integrating parasite intrinsic pathways with environmental signals for release into the bloodstream.Aditya S. PaulAlexandra MiliuJoao A. PauloJonathan M. GoldbergArianna M. BonillaLaurence BerryMarie SevenoCatherine Braun-BretonAziz L. KosberBrendan ElsworthJose S. N. ArriolaMaryse LebrunSteven P. GygiMauld H. LamarqueManoj T. DuraisinghNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aditya S. Paul Alexandra Miliu Joao A. Paulo Jonathan M. Goldberg Arianna M. Bonilla Laurence Berry Marie Seveno Catherine Braun-Breton Aziz L. Kosber Brendan Elsworth Jose S. N. Arriola Maryse Lebrun Steven P. Gygi Mauld H. Lamarque Manoj T. Duraisingh Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes
description	Plasmodium protein phosphatase PP1 is essential for the asexual proliferation of malaria parasites. Here the authors show that PP1 regulates egress of parasites from host red blood cells, integrating parasite intrinsic pathways with environmental signals for release into the bloodstream.
format	article
author	Aditya S. Paul Alexandra Miliu Joao A. Paulo Jonathan M. Goldberg Arianna M. Bonilla Laurence Berry Marie Seveno Catherine Braun-Breton Aziz L. Kosber Brendan Elsworth Jose S. N. Arriola Maryse Lebrun Steven P. Gygi Mauld H. Lamarque Manoj T. Duraisingh
author_facet	Aditya S. Paul Alexandra Miliu Joao A. Paulo Jonathan M. Goldberg Arianna M. Bonilla Laurence Berry Marie Seveno Catherine Braun-Breton Aziz L. Kosber Brendan Elsworth Jose S. N. Arriola Maryse Lebrun Steven P. Gygi Mauld H. Lamarque Manoj T. Duraisingh
author_sort	Aditya S. Paul
title	Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes
title_short	Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes
title_full	Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes
title_fullStr	Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes
title_full_unstemmed	Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes
title_sort	co-option of plasmodium falciparum pp1 for egress from host erythrocytes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7d2715bdc7484f8c88c035dcb70a2f3f
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Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

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