Il-10 signaling reduces survival in mouse models of synucleinopathy

Il-10 signaling reduces survival in mouse models of synucleinopathy

Abstract Parkinson’s disease (PD) and related synucleinopathies are characterized by chronic neuroinflammation leading to the premise that anti-inflammatory therapies could ameliorate synucleinopathy and associated sequelae. To test this idea, we used recombinant adeno-associated viruses (AAV) to ex...

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Bibliographic Details
Main Authors: Samuel G. Cockey, Karen N. McFarland, Emily J. Koller, Mieu M. T. Brooks, Elsa Gonzalez De La Cruz, Pedro E. Cruz, Carolina Ceballos-Diaz, Awilda M. Rosario, Yona R. Levites, David R. Borchelt, Todd E. Golde, Benoit I. Giasson, Paramita Chakrabarty
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Neurology. Diseases of the nervous system
RC346-429
Online Access:https://doaj.org/article/7d31e8435b0349f4ac0351ba14562121
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https://doaj.org/article/7d31e8435b0349f4ac0351ba14562121

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