Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.

In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed...

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Autores principales:	Chenglong Shi, Nana Lu, Yaru Qin, Mingdi Liu, Hongxia Li, Haichao Li
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7d3481100c3847388467785182cec1a4
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spelling	oai:doaj.org-article:7d3481100c3847388467785182cec1a42021-11-25T06:23:48ZStudy on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.1932-620310.1371/journal.pone.0247764https://doaj.org/article/7d3481100c3847388467785182cec1a42021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0247764https://doaj.org/toc/1932-6203In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed as 10 × 10 × 12 mm. Four groups of model samples were prepared by selective laser melting (SLM) and Ti6Al4V materials. The statics performance of the scaffolds was comprehensively evaluated by mechanical compression simulation and mechanical compression test, the manufacturing error of the scaffold samples were evaluated by scanning electron microscope (SEM), and the permeability of the scaffolds were predicted and evaluated by simulation analysis of computational fluid dynamics (CFD). The results show that the different distribution of porosity, pore size and pores of the elliptical scaffold have a certain influence on the mechanical properties and permeability of the scaffold, and the reasonable size and angle distribution of the elliptical pore can match the mechanical properties and permeability of the elliptical pore scaffold with human cancellous bone, which has great potential for research and application in the field of artificial bone scaffold.Chenglong ShiNana LuYaru QinMingdi LiuHongxia LiHaichao LiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 3, p e0247764 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chenglong Shi Nana Lu Yaru Qin Mingdi Liu Hongxia Li Haichao Li Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.
description	In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed as 10 × 10 × 12 mm. Four groups of model samples were prepared by selective laser melting (SLM) and Ti6Al4V materials. The statics performance of the scaffolds was comprehensively evaluated by mechanical compression simulation and mechanical compression test, the manufacturing error of the scaffold samples were evaluated by scanning electron microscope (SEM), and the permeability of the scaffolds were predicted and evaluated by simulation analysis of computational fluid dynamics (CFD). The results show that the different distribution of porosity, pore size and pores of the elliptical scaffold have a certain influence on the mechanical properties and permeability of the scaffold, and the reasonable size and angle distribution of the elliptical pore can match the mechanical properties and permeability of the elliptical pore scaffold with human cancellous bone, which has great potential for research and application in the field of artificial bone scaffold.
format	article
author	Chenglong Shi Nana Lu Yaru Qin Mingdi Liu Hongxia Li Haichao Li
author_facet	Chenglong Shi Nana Lu Yaru Qin Mingdi Liu Hongxia Li Haichao Li
author_sort	Chenglong Shi
title	Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.
title_short	Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.
title_full	Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.
title_fullStr	Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.
title_full_unstemmed	Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.
title_sort	study on mechanical properties and permeability of elliptical porous scaffold based on the slm manufactured medical ti6al4v.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/7d3481100c3847388467785182cec1a4
work_keys_str_mv	AT chenglongshi studyonmechanicalpropertiesandpermeabilityofellipticalporousscaffoldbasedontheslmmanufacturedmedicalti6al4v AT nanalu studyonmechanicalpropertiesandpermeabilityofellipticalporousscaffoldbasedontheslmmanufacturedmedicalti6al4v AT yaruqin studyonmechanicalpropertiesandpermeabilityofellipticalporousscaffoldbasedontheslmmanufacturedmedicalti6al4v AT mingdiliu studyonmechanicalpropertiesandpermeabilityofellipticalporousscaffoldbasedontheslmmanufacturedmedicalti6al4v AT hongxiali studyonmechanicalpropertiesandpermeabilityofellipticalporousscaffoldbasedontheslmmanufacturedmedicalti6al4v AT haichaoli studyonmechanicalpropertiesandpermeabilityofellipticalporousscaffoldbasedontheslmmanufacturedmedicalti6al4v
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Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.

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