Mediator complex interaction partners organize the transcriptional network that defines neural stem cells

The Mediator complex regulates transcription by connecting enhancers to promoters. Here, the authors purify Mediator from neural stem cells (NSCs), identify 75 novel protein-protein interaction partners and characterize the Mediator-interacting network that regulates transcription and establishes NS...

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Autores principales:	Marti Quevedo, Lize Meert, Mike R. Dekker, Dick H. W. Dekkers, Johannes H. Brandsma, Debbie L. C. van den Berg, Zeliha Ozgür, Wilfred F. J. van IJcken, Jeroen Demmers, Maarten Fornerod, Raymond A. Poot
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7d4ad1be2712463ca66eb3b3254a44a1
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spelling	oai:doaj.org-article:7d4ad1be2712463ca66eb3b3254a44a12021-12-02T17:02:11ZMediator complex interaction partners organize the transcriptional network that defines neural stem cells10.1038/s41467-019-10502-82041-1723https://doaj.org/article/7d4ad1be2712463ca66eb3b3254a44a12019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10502-8https://doaj.org/toc/2041-1723The Mediator complex regulates transcription by connecting enhancers to promoters. Here, the authors purify Mediator from neural stem cells (NSCs), identify 75 novel protein-protein interaction partners and characterize the Mediator-interacting network that regulates transcription and establishes NSC identity.Marti QuevedoLize MeertMike R. DekkerDick H. W. DekkersJohannes H. BrandsmaDebbie L. C. van den BergZeliha OzgürWilfred F. J. van IJckenJeroen DemmersMaarten FornerodRaymond A. PootNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marti Quevedo Lize Meert Mike R. Dekker Dick H. W. Dekkers Johannes H. Brandsma Debbie L. C. van den Berg Zeliha Ozgür Wilfred F. J. van IJcken Jeroen Demmers Maarten Fornerod Raymond A. Poot Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
description	The Mediator complex regulates transcription by connecting enhancers to promoters. Here, the authors purify Mediator from neural stem cells (NSCs), identify 75 novel protein-protein interaction partners and characterize the Mediator-interacting network that regulates transcription and establishes NSC identity.
format	article
author	Marti Quevedo Lize Meert Mike R. Dekker Dick H. W. Dekkers Johannes H. Brandsma Debbie L. C. van den Berg Zeliha Ozgür Wilfred F. J. van IJcken Jeroen Demmers Maarten Fornerod Raymond A. Poot
author_facet	Marti Quevedo Lize Meert Mike R. Dekker Dick H. W. Dekkers Johannes H. Brandsma Debbie L. C. van den Berg Zeliha Ozgür Wilfred F. J. van IJcken Jeroen Demmers Maarten Fornerod Raymond A. Poot
author_sort	Marti Quevedo
title	Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
title_short	Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
title_full	Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
title_fullStr	Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
title_full_unstemmed	Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
title_sort	mediator complex interaction partners organize the transcriptional network that defines neural stem cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7d4ad1be2712463ca66eb3b3254a44a1
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Mediator complex interaction partners organize the transcriptional network that defines neural stem cells

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