Hepatitis C virus (HCV) evades NKG2D-dependent NK cell responses through NS5A-mediated imbalance of inflammatory cytokines.

Understanding how hepatitis C virus (HCV) induces and circumvents the host's natural killer (NK) cell-mediated immunity is of critical importance in efforts to design effective therapeutics. We report here the decreased expression of the NKG2D activating receptor as a novel strategy adopted by...

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Auteurs principaux: Damien Sène, Franck Levasseur, Michal Abel, Marion Lambert, Xavier Camous, Céline Hernandez, Véronique Pène, Arielle R Rosenberg, Evelyne Jouvin-Marche, Patrice N Marche, Patrice Cacoub, Sophie Caillat-Zucman
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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Accès en ligne:https://doaj.org/article/7d4b8c71da6d4f89bb063c44cd7e01d1
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