DEVELOPMENT OF A REAL-TIME RT-PCR-BASED TEST PANEL FOR ASSESSMENT OF CYTOKINE PROFILE IN MONONUCLEAR CELLS FROM BLOOD AND SYNOVIAL FLUID IN RHEUMATOID ARTHRITIS

DEVELOPMENT OF A REAL-TIME RT-PCR-BASED TEST PANEL FOR ASSESSMENT OF CYTOKINE PROFILE IN MONONUCLEAR CELLS FROM BLOOD AND SYNOVIAL FLUID IN RHEUMATOID ARTHRITIS

Abstract. An imbalance between pro- and anti-inflammatory cytokine synthesis plays a crucial role in pathogenesis of rheumatoid arthritis (RA), including erosive joint lesions. Differences in cytokine profiles of RA patients are sufficiently investigated. However, possible interrelations between cyt...

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Bibliographic Details
Main Authors: D. Yu. Trofimov, O. V. Burmenskaya, E. I. Bateneva, L. P. Alexeev, E. L. Nasonov, E. N. Alexandrova, A. A. Novikov
Format: article
Language:RU
Published: SPb RAACI 2014
Subjects:
rt-pcr
cytokine profile
mononuclear cells
rheumatoid arthritis
tnfα
il-1β
il-6
il-8
il-17
il-15
il-10
ifnγ
il-4
il-2
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/7d4d8caa6c6641bf8ab4fd5b09a0c612
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