Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors

Here, the authors model the collecting duct system in kidneys by taking ureteric bud (UB) progenitor cells from both mouse and human primary tissues, as well as from hESC and hiPSC to generate organoids, which can model congenital anomalies of the kidney and urinary tract.

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Autores principales:	Zipeng Zeng, Biao Huang, Riana K. Parvez, Yidan Li, Jyunhao Chen, Ariel C. Vonk, Matthew E. Thornton, Tadrushi Patel, Elisabeth A. Rutledge, Albert D. Kim, Jingying Yu, Brendan H. Grubbs, Jill A. McMahon, Nuria M. Pastor-Soler, Kenneth R. Hallows, Andrew P. McMahon, Zhongwei Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7d4f8c87de714171bfaad82e1c28c88c
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spelling	oai:doaj.org-article:7d4f8c87de714171bfaad82e1c28c88c2021-12-02T16:04:33ZGeneration of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors10.1038/s41467-021-23911-52041-1723https://doaj.org/article/7d4f8c87de714171bfaad82e1c28c88c2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23911-5https://doaj.org/toc/2041-1723Here, the authors model the collecting duct system in kidneys by taking ureteric bud (UB) progenitor cells from both mouse and human primary tissues, as well as from hESC and hiPSC to generate organoids, which can model congenital anomalies of the kidney and urinary tract.Zipeng ZengBiao HuangRiana K. ParvezYidan LiJyunhao ChenAriel C. VonkMatthew E. ThorntonTadrushi PatelElisabeth A. RutledgeAlbert D. KimJingying YuBrendan H. GrubbsJill A. McMahonNuria M. Pastor-SolerKenneth R. HallowsAndrew P. McMahonZhongwei LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zipeng Zeng Biao Huang Riana K. Parvez Yidan Li Jyunhao Chen Ariel C. Vonk Matthew E. Thornton Tadrushi Patel Elisabeth A. Rutledge Albert D. Kim Jingying Yu Brendan H. Grubbs Jill A. McMahon Nuria M. Pastor-Soler Kenneth R. Hallows Andrew P. McMahon Zhongwei Li Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors
description	Here, the authors model the collecting duct system in kidneys by taking ureteric bud (UB) progenitor cells from both mouse and human primary tissues, as well as from hESC and hiPSC to generate organoids, which can model congenital anomalies of the kidney and urinary tract.
format	article
author	Zipeng Zeng Biao Huang Riana K. Parvez Yidan Li Jyunhao Chen Ariel C. Vonk Matthew E. Thornton Tadrushi Patel Elisabeth A. Rutledge Albert D. Kim Jingying Yu Brendan H. Grubbs Jill A. McMahon Nuria M. Pastor-Soler Kenneth R. Hallows Andrew P. McMahon Zhongwei Li
author_facet	Zipeng Zeng Biao Huang Riana K. Parvez Yidan Li Jyunhao Chen Ariel C. Vonk Matthew E. Thornton Tadrushi Patel Elisabeth A. Rutledge Albert D. Kim Jingying Yu Brendan H. Grubbs Jill A. McMahon Nuria M. Pastor-Soler Kenneth R. Hallows Andrew P. McMahon Zhongwei Li
author_sort	Zipeng Zeng
title	Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors
title_short	Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors
title_full	Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors
title_fullStr	Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors
title_full_unstemmed	Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors
title_sort	generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7d4f8c87de714171bfaad82e1c28c88c
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Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors

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