Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling

Astrocytes can engulf axonal debris in the developing brain. However, the mechanisms regulating astrocyte recruitment to the proper axons is unclear. Here, the authors identify Orion as a signal for astrocyte infiltration and engulfment to the mushroom bodies in the Drosophila developing brain.

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Autores principales: Ana Boulanger, Camille Thinat, Stephan Züchner, Lee G. Fradkin, Hugues Lortat-Jacob, Jean-Maurice Dura
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7d50d2bfd54946bcb09d66fa9897cc06
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spelling oai:doaj.org-article:7d50d2bfd54946bcb09d66fa9897cc062021-12-02T16:36:00ZAxonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling10.1038/s41467-021-22054-x2041-1723https://doaj.org/article/7d50d2bfd54946bcb09d66fa9897cc062021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22054-xhttps://doaj.org/toc/2041-1723Astrocytes can engulf axonal debris in the developing brain. However, the mechanisms regulating astrocyte recruitment to the proper axons is unclear. Here, the authors identify Orion as a signal for astrocyte infiltration and engulfment to the mushroom bodies in the Drosophila developing brain.Ana BoulangerCamille ThinatStephan ZüchnerLee G. FradkinHugues Lortat-JacobJean-Maurice DuraNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ana Boulanger
Camille Thinat
Stephan Züchner
Lee G. Fradkin
Hugues Lortat-Jacob
Jean-Maurice Dura
Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
description Astrocytes can engulf axonal debris in the developing brain. However, the mechanisms regulating astrocyte recruitment to the proper axons is unclear. Here, the authors identify Orion as a signal for astrocyte infiltration and engulfment to the mushroom bodies in the Drosophila developing brain.
format article
author Ana Boulanger
Camille Thinat
Stephan Züchner
Lee G. Fradkin
Hugues Lortat-Jacob
Jean-Maurice Dura
author_facet Ana Boulanger
Camille Thinat
Stephan Züchner
Lee G. Fradkin
Hugues Lortat-Jacob
Jean-Maurice Dura
author_sort Ana Boulanger
title Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
title_short Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
title_full Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
title_fullStr Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
title_full_unstemmed Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
title_sort axonal chemokine-like orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7d50d2bfd54946bcb09d66fa9897cc06
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AT camillethinat axonalchemokinelikeorioninducesastrocyteinfiltrationandengulfmentduringmushroombodyneuronalremodeling
AT stephanzuchner axonalchemokinelikeorioninducesastrocyteinfiltrationandengulfmentduringmushroombodyneuronalremodeling
AT leegfradkin axonalchemokinelikeorioninducesastrocyteinfiltrationandengulfmentduringmushroombodyneuronalremodeling
AT hugueslortatjacob axonalchemokinelikeorioninducesastrocyteinfiltrationandengulfmentduringmushroombodyneuronalremodeling
AT jeanmauricedura axonalchemokinelikeorioninducesastrocyteinfiltrationandengulfmentduringmushroombodyneuronalremodeling
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