JRAB/MICAL-L2 undergoes liquid–liquid phase separation to form tubular recycling endosomes
Sakane et al. demonstrate that JRAB/MICAL-L2, an effector protein of Rab8 and Rab13, induces endosomal tubulation in HeLa cells depending on its closed conformation caused by an activated Rab8A. JRAB/MICAL-L2 undergoes liquid-liquid phase separation when overexpressed, which precedes its interaction...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/7d59caf0ee0141aaa9aefc5a48b29c24 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|