Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila

Low doses of harmful chemicals such as oxidants can have beneficial effects, in some cases mediated by increased expression of stress response genes. In this study, the authors show that low-dose oxidants increase the longevity of Drosophila via a different mechanism, remodelling of the microbiome.

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Detalles Bibliográficos
Autores principales: Fumiaki Obata, Clara O. Fons, Alex P. Gould
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7d5be31fd3d64703a2eb972bcf6be1bf
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Descripción
Sumario:Low doses of harmful chemicals such as oxidants can have beneficial effects, in some cases mediated by increased expression of stress response genes. In this study, the authors show that low-dose oxidants increase the longevity of Drosophila via a different mechanism, remodelling of the microbiome.