Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila

Low doses of harmful chemicals such as oxidants can have beneficial effects, in some cases mediated by increased expression of stress response genes. In this study, the authors show that low-dose oxidants increase the longevity of Drosophila via a different mechanism, remodelling of the microbiome.

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Autores principales:	Fumiaki Obata, Clara O. Fons, Alex P. Gould
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7d5be31fd3d64703a2eb972bcf6be1bf
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spelling	oai:doaj.org-article:7d5be31fd3d64703a2eb972bcf6be1bf2021-12-02T14:41:28ZEarly-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila10.1038/s41467-018-03070-w2041-1723https://doaj.org/article/7d5be31fd3d64703a2eb972bcf6be1bf2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03070-whttps://doaj.org/toc/2041-1723Low doses of harmful chemicals such as oxidants can have beneficial effects, in some cases mediated by increased expression of stress response genes. In this study, the authors show that low-dose oxidants increase the longevity of Drosophila via a different mechanism, remodelling of the microbiome.Fumiaki ObataClara O. FonsAlex P. GouldNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fumiaki Obata Clara O. Fons Alex P. Gould Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila
description	Low doses of harmful chemicals such as oxidants can have beneficial effects, in some cases mediated by increased expression of stress response genes. In this study, the authors show that low-dose oxidants increase the longevity of Drosophila via a different mechanism, remodelling of the microbiome.
format	article
author	Fumiaki Obata Clara O. Fons Alex P. Gould
author_facet	Fumiaki Obata Clara O. Fons Alex P. Gould
author_sort	Fumiaki Obata
title	Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila
title_short	Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila
title_full	Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila
title_fullStr	Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila
title_full_unstemmed	Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila
title_sort	early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in drosophila
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7d5be31fd3d64703a2eb972bcf6be1bf
work_keys_str_mv	AT fumiakiobata earlylifeexposuretolowdoseoxidantscanincreaselongevityviamicrobiomeremodellingindrosophila AT claraofons earlylifeexposuretolowdoseoxidantscanincreaselongevityviamicrobiomeremodellingindrosophila AT alexpgould earlylifeexposuretolowdoseoxidantscanincreaselongevityviamicrobiomeremodellingindrosophila
_version_	1718389879433330688

Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila

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