BiP and Multiple DNAJ Molecular Chaperones in the Endoplasmic Reticulum Are Required for Efficient Simian Virus 40 Infection

BiP and Multiple DNAJ Molecular Chaperones in the Endoplasmic Reticulum Are Required for Efficient Simian Virus 40 Infection

ABSTRACT Simian virus 40 (SV40) is a nonenveloped DNA virus that traffics through the endoplasmic reticulum (ER) en route to the nucleus, but the mechanisms of capsid disassembly and ER exit are poorly understood. We conducted an unbiased RNA interference screen to identify cellular genes required f...

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Bibliographic Details
Main Authors: Edward C. Goodwin, Alex Lipovsky, Takamasa Inoue, Thomas G. Magaldi, Anne P. B. Edwards, Kristin E. Y. Van Goor, Adrienne W. Paton, James C. Paton, Walter J. Atwood, Billy Tsai, Daniel DiMaio
Format: article
Language:EN
Published: American Society for Microbiology 2011
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/7d5ff50acbcd43f9ac63ba8b338523b9
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