BiP and Multiple DNAJ Molecular Chaperones in the Endoplasmic Reticulum Are Required for Efficient Simian Virus 40 Infection
ABSTRACT Simian virus 40 (SV40) is a nonenveloped DNA virus that traffics through the endoplasmic reticulum (ER) en route to the nucleus, but the mechanisms of capsid disassembly and ER exit are poorly understood. We conducted an unbiased RNA interference screen to identify cellular genes required f...
Enregistré dans:
Auteurs principaux: | Edward C. Goodwin, Alex Lipovsky, Takamasa Inoue, Thomas G. Magaldi, Anne P. B. Edwards, Kristin E. Y. Van Goor, Adrienne W. Paton, James C. Paton, Walter J. Atwood, Billy Tsai, Daniel DiMaio |
---|---|
Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2011
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/7d5ff50acbcd43f9ac63ba8b338523b9 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP
par: Yahui Yan, et autres
Publié: (2019) -
Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD
par: Joel Fauser, et autres
Publié: (2021) -
A large and intact viral particle penetrates the endoplasmic reticulum membrane to reach the cytosol.
par: Takamasa Inoue, et autres
Publié: (2011) -
Interaction between Simian Virus 40 Major Capsid Protein VP1 and Cell Surface Ganglioside GM1 Triggers Vacuole Formation
par: Yong Luo, et autres
Publié: (2016) -
The molecular chaperone binding protein BiP prevents leaf dehydration-induced cellular homeostasis disruption.
par: Humberto H Carvalho, et autres
Publié: (2014)