Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3
Cerebrospinal fluid-contacting (CSF-c) cells line the central canal of the vertebrate spinal cord yet their function remains unknown. Here, Javaland et al. show that CSF-c neurons in the lamprey respond to mechanical stimulation and lowered pH, effects likely mediated by ASIC3-channels.
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Nature Portfolio
2016
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oai:doaj.org-article:7d67035007034d0a85831ed99ee260892021-12-02T17:32:23ZCiliated neurons lining the central canal sense both fluid movement and pH through ASIC310.1038/ncomms100022041-1723https://doaj.org/article/7d67035007034d0a85831ed99ee260892016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10002https://doaj.org/toc/2041-1723Cerebrospinal fluid-contacting (CSF-c) cells line the central canal of the vertebrate spinal cord yet their function remains unknown. Here, Javaland et al. show that CSF-c neurons in the lamprey respond to mechanical stimulation and lowered pH, effects likely mediated by ASIC3-channels.Elham JalalvandBrita RobertsonPeter WallénSten GrillnerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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Science Q Elham Jalalvand Brita Robertson Peter Wallén Sten Grillner Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3 |
description |
Cerebrospinal fluid-contacting (CSF-c) cells line the central canal of the vertebrate spinal cord yet their function remains unknown. Here, Javaland et al. show that CSF-c neurons in the lamprey respond to mechanical stimulation and lowered pH, effects likely mediated by ASIC3-channels. |
format |
article |
author |
Elham Jalalvand Brita Robertson Peter Wallén Sten Grillner |
author_facet |
Elham Jalalvand Brita Robertson Peter Wallén Sten Grillner |
author_sort |
Elham Jalalvand |
title |
Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3 |
title_short |
Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3 |
title_full |
Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3 |
title_fullStr |
Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3 |
title_full_unstemmed |
Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3 |
title_sort |
ciliated neurons lining the central canal sense both fluid movement and ph through asic3 |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/7d67035007034d0a85831ed99ee26089 |
work_keys_str_mv |
AT elhamjalalvand ciliatedneuronsliningthecentralcanalsensebothfluidmovementandphthroughasic3 AT britarobertson ciliatedneuronsliningthecentralcanalsensebothfluidmovementandphthroughasic3 AT peterwallen ciliatedneuronsliningthecentralcanalsensebothfluidmovementandphthroughasic3 AT stengrillner ciliatedneuronsliningthecentralcanalsensebothfluidmovementandphthroughasic3 |
_version_ |
1718380317275848704 |