Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.

Nuclear Factor kappa B (NF-κB) is a key mediator of normal immune response but contributes to aggressive cancer cell phenotypes when aberrantly activated. Here we present evidence that the Inhibitor of Growth 4 (ING4) tumor suppressor negatively regulates NF-κB in breast cancer. We surveyed primary...

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Autores principales: Sara A Byron, Elizabeth Min, Tanya S Thal, Galen Hostetter, Aprill T Watanabe, David O Azorsa, Tanya H Little, Coya Tapia, Suwon Kim
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/7d675166899b403d8971cfe903ed08a5
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