STUDY OF CYTOKINE PROFILE IN INFLUENZA COMPLICATED BY PNEUMONIA
The goal of present study was to perform a comparative evaluation of cytokine levels in blood of 123 patients with uncomplicated influenza versus a group of cases complicated by subsequent pneumonia. Higher levels of TNFα, IL-10, IL-6, IL-8 and lower levels of IFNγ were found in blood serum of those...
Guardado en:
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
SPb RAACI
2014
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/7d7039142e9c4eb28de30b0bd1ff671f |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | The goal of present study was to perform a comparative evaluation of cytokine levels in blood of 123 patients with uncomplicated influenza versus a group of cases complicated by subsequent pneumonia. Higher levels of TNFα, IL-10, IL-6, IL-8 and lower levels of IFNγ were found in blood serum of those patients who developed pneumonia during acute phase of influenza. We have revealed a correlation between the severity and duration of symptoms of both uncomplicated and pneumonia-conplicated flu, and serum concentrations of proinflammatory (TNFα, IL-1β, IL-6, IL-8) and anti-inflammatory cytokines (IL-1rа, и IL-10), as well as with indexes of interferon profile (antiIFNα, IFNα и IFNγ) in the patients. |
|---|