Rationally designed synthetic protein hydrogels with predictable mechanical properties

Mechanical properties of protein hydrogels are critical to mimic natural tissue but correlating bulk properties on the molecular level remains challenging. Here the authors show that the hierarchy of crosslinkers and load-bearing modules on a molecular level defines the mechanical properties of the...

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Auteurs principaux:	Junhua Wu, Pengfei Li, Chenling Dong, Heting Jiang, Bin Xue, Xiang Gao, Meng Qin, Wei Wang, Bin Chen, Yi Cao
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/7d73dd7caa7c46a58297a09fde39dee9
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spelling	oai:doaj.org-article:7d73dd7caa7c46a58297a09fde39dee92021-12-02T14:39:23ZRationally designed synthetic protein hydrogels with predictable mechanical properties10.1038/s41467-018-02917-62041-1723https://doaj.org/article/7d73dd7caa7c46a58297a09fde39dee92018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02917-6https://doaj.org/toc/2041-1723Mechanical properties of protein hydrogels are critical to mimic natural tissue but correlating bulk properties on the molecular level remains challenging. Here the authors show that the hierarchy of crosslinkers and load-bearing modules on a molecular level defines the mechanical properties of the hydrogel.Junhua WuPengfei LiChenling DongHeting JiangBin XueXiang GaoMeng QinWei WangBin ChenYi CaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Junhua Wu Pengfei Li Chenling Dong Heting Jiang Bin Xue Xiang Gao Meng Qin Wei Wang Bin Chen Yi Cao Rationally designed synthetic protein hydrogels with predictable mechanical properties
description	Mechanical properties of protein hydrogels are critical to mimic natural tissue but correlating bulk properties on the molecular level remains challenging. Here the authors show that the hierarchy of crosslinkers and load-bearing modules on a molecular level defines the mechanical properties of the hydrogel.
format	article
author	Junhua Wu Pengfei Li Chenling Dong Heting Jiang Bin Xue Xiang Gao Meng Qin Wei Wang Bin Chen Yi Cao
author_facet	Junhua Wu Pengfei Li Chenling Dong Heting Jiang Bin Xue Xiang Gao Meng Qin Wei Wang Bin Chen Yi Cao
author_sort	Junhua Wu
title	Rationally designed synthetic protein hydrogels with predictable mechanical properties
title_short	Rationally designed synthetic protein hydrogels with predictable mechanical properties
title_full	Rationally designed synthetic protein hydrogels with predictable mechanical properties
title_fullStr	Rationally designed synthetic protein hydrogels with predictable mechanical properties
title_full_unstemmed	Rationally designed synthetic protein hydrogels with predictable mechanical properties
title_sort	rationally designed synthetic protein hydrogels with predictable mechanical properties
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7d73dd7caa7c46a58297a09fde39dee9
work_keys_str_mv	AT junhuawu rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT pengfeili rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT chenlingdong rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT hetingjiang rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT binxue rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT xianggao rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT mengqin rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT weiwang rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT binchen rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties AT yicao rationallydesignedsyntheticproteinhydrogelswithpredictablemechanicalproperties
_version_	1718390664195997696

Rationally designed synthetic protein hydrogels with predictable mechanical properties

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