Light control of the peptide-loading complex synchronizes antigen translocation and MHC I trafficking

Brunnberg et al. establish a protocol that enables them to optically control translocation of the transporter associated with antigen processing (TAP), which plays a role in delivering proteasomal degradation products into the ER lumen. Their versatile approach provides insights into TAP function in...

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Autores principales: Jamina Brunnberg, Valentina Herbring, Esteban Günther Castillo, Heike Krüger, Ralph Wieneke, Robert Tampé
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7d742d0a34ce4d60b7958af938b31d53
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