Light control of the peptide-loading complex synchronizes antigen translocation and MHC I trafficking

Brunnberg et al. establish a protocol that enables them to optically control translocation of the transporter associated with antigen processing (TAP), which plays a role in delivering proteasomal degradation products into the ER lumen. Their versatile approach provides insights into TAP function in...

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Auteurs principaux: Jamina Brunnberg, Valentina Herbring, Esteban Günther Castillo, Heike Krüger, Ralph Wieneke, Robert Tampé
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/7d742d0a34ce4d60b7958af938b31d53
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