Tonsillar Cancer with High CD8<sup>+</sup> T-Cell Infiltration Features Increased Levels of Dendritic Cells and Transcriptional Regulation Associated with an Inflamed Tumor Microenvironment

Tonsillar Cancer with High CD8<sup>+</sup> T-Cell Infiltration Features Increased Levels of Dendritic Cells and Transcriptional Regulation Associated with an Inflamed Tumor Microenvironment

Human papillomavirus (HPV) is the main causal agent of tonsillar cancer (TC) and HPV<sup>+</sup> TC has a favorable prognosis compared to HPV<sup>−</sup> disease. In this study, we examined aspects of the tumor microenvironment of TC, focusing on T-cells, dendritic cells (DC)...

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Détails bibliographiques
Auteurs principaux: David Gomez Jimenez, Aastha Sobti, David Askmyr, Christina Sakellariou, Sofia Carreira Santos, Sabine Swoboda, Ola Forslund, Lennart Greiff, Malin Lindstedt
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
tonsillar cancer
human papillomavirus
tumor microenvironment
CD8<sup>+</sup> T-cells
dendritic cells
macrophages
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Accès en ligne:https://doaj.org/article/7d76c96c44d246ef8232b08db6eeb50b
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https://doaj.org/article/7d76c96c44d246ef8232b08db6eeb50b

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