Electronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes

Abstract The exciting discovery of the semiconducting-like properties of deoxyribonucleic acid (DNA) and its potential applications in molecular genetics and diagnostics in recent times has resulted in a paradigm shift in biophysics research. Recent studies in our laboratory provide a platform towar...

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Autores principales:	Nastaran Rizan, Chan Yen Yew, Maryam Rajabpour Niknam, Jegenathan Krishnasamy, Subha Bhassu, Goh Zee Hong, Sridevi Devadas, Mohamed Shariff Mohd Din, Hairul Anuar Tajuddin, Rofina Yasmin Othman, Siew Moi Phang, Mitsumasa Iwamoto, Vengadesh Periasamy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7d793e2dcaea4ddba1eaf36fa87dbed6
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spelling	oai:doaj.org-article:7d793e2dcaea4ddba1eaf36fa87dbed62021-12-02T15:08:37ZElectronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes10.1038/s41598-017-18825-62045-2322https://doaj.org/article/7d793e2dcaea4ddba1eaf36fa87dbed62018-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-18825-6https://doaj.org/toc/2045-2322Abstract The exciting discovery of the semiconducting-like properties of deoxyribonucleic acid (DNA) and its potential applications in molecular genetics and diagnostics in recent times has resulted in a paradigm shift in biophysics research. Recent studies in our laboratory provide a platform towards detecting charge transfer mechanism and understanding the electronic properties of DNA based on the sequence-specific electronic response, which can be applied as an alternative to identify or detect DNA. In this study, we demonstrate a novel method for identification of DNA from different shrimp viruses and bacteria using electronic properties of DNA obtained from both negative and positive bias regions in current-voltage (I–V) profiles. Characteristic electronic properties were calculated and used for quantification and further understanding in the identification process. Aquaculture in shrimp industry is a fast-growing food sector throughout the world. However, shrimp culture in many Asian countries faced a huge economic loss due to disease outbreaks. Scientists have been using specific established methods for detecting shrimp infection, but those methods do have their significant drawbacks due to many inherent factors. As such, we believe that this simple, rapid, sensitive and cost-effective tool can be used for detection and identification of DNA from different shrimp viruses and bacteria.Nastaran RizanChan Yen YewMaryam Rajabpour NiknamJegenathan KrishnasamySubha BhassuGoh Zee HongSridevi DevadasMohamed Shariff Mohd DinHairul Anuar TajuddinRofina Yasmin OthmanSiew Moi PhangMitsumasa IwamotoVengadesh PeriasamyNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Nastaran Rizan Chan Yen Yew Maryam Rajabpour Niknam Jegenathan Krishnasamy Subha Bhassu Goh Zee Hong Sridevi Devadas Mohamed Shariff Mohd Din Hairul Anuar Tajuddin Rofina Yasmin Othman Siew Moi Phang Mitsumasa Iwamoto Vengadesh Periasamy Electronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes
description	Abstract The exciting discovery of the semiconducting-like properties of deoxyribonucleic acid (DNA) and its potential applications in molecular genetics and diagnostics in recent times has resulted in a paradigm shift in biophysics research. Recent studies in our laboratory provide a platform towards detecting charge transfer mechanism and understanding the electronic properties of DNA based on the sequence-specific electronic response, which can be applied as an alternative to identify or detect DNA. In this study, we demonstrate a novel method for identification of DNA from different shrimp viruses and bacteria using electronic properties of DNA obtained from both negative and positive bias regions in current-voltage (I–V) profiles. Characteristic electronic properties were calculated and used for quantification and further understanding in the identification process. Aquaculture in shrimp industry is a fast-growing food sector throughout the world. However, shrimp culture in many Asian countries faced a huge economic loss due to disease outbreaks. Scientists have been using specific established methods for detecting shrimp infection, but those methods do have their significant drawbacks due to many inherent factors. As such, we believe that this simple, rapid, sensitive and cost-effective tool can be used for detection and identification of DNA from different shrimp viruses and bacteria.
format	article
author	Nastaran Rizan Chan Yen Yew Maryam Rajabpour Niknam Jegenathan Krishnasamy Subha Bhassu Goh Zee Hong Sridevi Devadas Mohamed Shariff Mohd Din Hairul Anuar Tajuddin Rofina Yasmin Othman Siew Moi Phang Mitsumasa Iwamoto Vengadesh Periasamy
author_facet	Nastaran Rizan Chan Yen Yew Maryam Rajabpour Niknam Jegenathan Krishnasamy Subha Bhassu Goh Zee Hong Sridevi Devadas Mohamed Shariff Mohd Din Hairul Anuar Tajuddin Rofina Yasmin Othman Siew Moi Phang Mitsumasa Iwamoto Vengadesh Periasamy
author_sort	Nastaran Rizan
title	Electronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes
title_short	Electronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes
title_full	Electronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes
title_fullStr	Electronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes
title_full_unstemmed	Electronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes
title_sort	electronic properties of synthetic shrimp pathogens-derived dna schottky diodes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7d793e2dcaea4ddba1eaf36fa87dbed6
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Electronic Properties of Synthetic Shrimp Pathogens-derived DNA Schottky Diodes

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