Freeze-frame imaging of synaptic activity using SynTagMA

Calcium imaging has been used to visualize the activity of individual synapses, but cannot be scaled up to monitor thousands of synapses in tissue. Here, the authors present genetic tools that can be photoconverted from green to red to create a map of active synapses.

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Autores principales:	Alberto Perez-Alvarez, Brenna C. Fearey, Ryan J. O’Toole, Wei Yang, Ignacio Arganda-Carreras, Paul J. Lamothe-Molina, Benjamien Moeyaert, Manuel A. Mohr, Lauren C. Panzera, Christian Schulze, Eric R. Schreiter, J. Simon Wiegert, Christine E. Gee, Michael B. Hoppa, Thomas G. Oertner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7d7a281a0ac548d19a0654bd5702913e
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spelling	oai:doaj.org-article:7d7a281a0ac548d19a0654bd5702913e2021-12-02T15:52:53ZFreeze-frame imaging of synaptic activity using SynTagMA10.1038/s41467-020-16315-42041-1723https://doaj.org/article/7d7a281a0ac548d19a0654bd5702913e2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16315-4https://doaj.org/toc/2041-1723Calcium imaging has been used to visualize the activity of individual synapses, but cannot be scaled up to monitor thousands of synapses in tissue. Here, the authors present genetic tools that can be photoconverted from green to red to create a map of active synapses.Alberto Perez-AlvarezBrenna C. FeareyRyan J. O’TooleWei YangIgnacio Arganda-CarrerasPaul J. Lamothe-MolinaBenjamien MoeyaertManuel A. MohrLauren C. PanzeraChristian SchulzeEric R. SchreiterJ. Simon WiegertChristine E. GeeMichael B. HoppaThomas G. OertnerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alberto Perez-Alvarez Brenna C. Fearey Ryan J. O’Toole Wei Yang Ignacio Arganda-Carreras Paul J. Lamothe-Molina Benjamien Moeyaert Manuel A. Mohr Lauren C. Panzera Christian Schulze Eric R. Schreiter J. Simon Wiegert Christine E. Gee Michael B. Hoppa Thomas G. Oertner Freeze-frame imaging of synaptic activity using SynTagMA
description	Calcium imaging has been used to visualize the activity of individual synapses, but cannot be scaled up to monitor thousands of synapses in tissue. Here, the authors present genetic tools that can be photoconverted from green to red to create a map of active synapses.
format	article
author	Alberto Perez-Alvarez Brenna C. Fearey Ryan J. O’Toole Wei Yang Ignacio Arganda-Carreras Paul J. Lamothe-Molina Benjamien Moeyaert Manuel A. Mohr Lauren C. Panzera Christian Schulze Eric R. Schreiter J. Simon Wiegert Christine E. Gee Michael B. Hoppa Thomas G. Oertner
author_facet	Alberto Perez-Alvarez Brenna C. Fearey Ryan J. O’Toole Wei Yang Ignacio Arganda-Carreras Paul J. Lamothe-Molina Benjamien Moeyaert Manuel A. Mohr Lauren C. Panzera Christian Schulze Eric R. Schreiter J. Simon Wiegert Christine E. Gee Michael B. Hoppa Thomas G. Oertner
author_sort	Alberto Perez-Alvarez
title	Freeze-frame imaging of synaptic activity using SynTagMA
title_short	Freeze-frame imaging of synaptic activity using SynTagMA
title_full	Freeze-frame imaging of synaptic activity using SynTagMA
title_fullStr	Freeze-frame imaging of synaptic activity using SynTagMA
title_full_unstemmed	Freeze-frame imaging of synaptic activity using SynTagMA
title_sort	freeze-frame imaging of synaptic activity using syntagma
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7d7a281a0ac548d19a0654bd5702913e
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Freeze-frame imaging of synaptic activity using SynTagMA

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