NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates

Astrocytes are important players in ischemic stroke. Here, the authors use single nuclei transcriptomics to characterise marmoset astrocytes following brain injury. At functional level, they show that NogoAexpressing astrocytes limit macrophage infiltration.

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Autores principales:	Anthony G. Boghdadi, Joshua Spurrier, Leon Teo, Mingfeng Li, Mario Skarica, Benjamin Cao, William C. Kwan, Tobias D. Merson, Susan K. Nilsson, Nenad Sestan, Stephen M. Strittmatter, James A. Bourne
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7d7d2c9ecae3430ebc0d5c40de26ce6f
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spelling	oai:doaj.org-article:7d7d2c9ecae3430ebc0d5c40de26ce6f2021-11-28T12:33:52ZNogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates10.1038/s41467-021-27245-02041-1723https://doaj.org/article/7d7d2c9ecae3430ebc0d5c40de26ce6f2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27245-0https://doaj.org/toc/2041-1723Astrocytes are important players in ischemic stroke. Here, the authors use single nuclei transcriptomics to characterise marmoset astrocytes following brain injury. At functional level, they show that NogoAexpressing astrocytes limit macrophage infiltration.Anthony G. BoghdadiJoshua SpurrierLeon TeoMingfeng LiMario SkaricaBenjamin CaoWilliam C. KwanTobias D. MersonSusan K. NilssonNenad SestanStephen M. StrittmatterJames A. BourneNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anthony G. Boghdadi Joshua Spurrier Leon Teo Mingfeng Li Mario Skarica Benjamin Cao William C. Kwan Tobias D. Merson Susan K. Nilsson Nenad Sestan Stephen M. Strittmatter James A. Bourne NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates
description	Astrocytes are important players in ischemic stroke. Here, the authors use single nuclei transcriptomics to characterise marmoset astrocytes following brain injury. At functional level, they show that NogoAexpressing astrocytes limit macrophage infiltration.
format	article
author	Anthony G. Boghdadi Joshua Spurrier Leon Teo Mingfeng Li Mario Skarica Benjamin Cao William C. Kwan Tobias D. Merson Susan K. Nilsson Nenad Sestan Stephen M. Strittmatter James A. Bourne
author_facet	Anthony G. Boghdadi Joshua Spurrier Leon Teo Mingfeng Li Mario Skarica Benjamin Cao William C. Kwan Tobias D. Merson Susan K. Nilsson Nenad Sestan Stephen M. Strittmatter James A. Bourne
author_sort	Anthony G. Boghdadi
title	NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates
title_short	NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates
title_full	NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates
title_fullStr	NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates
title_full_unstemmed	NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates
title_sort	nogoa-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7d7d2c9ecae3430ebc0d5c40de26ce6f
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NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates

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