Matriptase-2 deficiency protects from obesity by modulating iron homeostasis

Matriptase-2 deficiency protects from obesity by modulating iron homeostasis

Iron homeostasis dysfunctions have been associated with several metabolic disorders including obesity, steatosis and diabetes. Here the authors demonstrate that the hepcidin repressor matriptase-2 regulates adiposity and its deficiency protects mice against obesity and promotes lipolysis.

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Autores principales: Alicia R. Folgueras, Sandra Freitas-Rodríguez, Andrew J. Ramsay, Cecilia Garabaya, Francisco Rodríguez, Gloria Velasco, Carlos López-Otín
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/7d9380d8e26744d9bacd18d51dfcfc31
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