Extra-coding RNAs regulate neuronal DNA methylation dynamics

DNA methylation in the brain is a dynamic process, but gene-specific regulation of this process is poorly understood. Here, Day and colleagues show that extra-coding RNAs interact with DNA methyltransferases and regulate neuronal DNA methylation to control gene expression in locus-specific manner in...

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Autores principales: Katherine E. Savell, Nancy V. N. Gallus, Rhiana C. Simon, Jordan A. Brown, Jasmin S. Revanna, Mary Katherine Osborn, Esther Y. Song, John J. O’Malley, Christian T. Stackhouse, Allison Norvil, Humaira Gowher, J. David Sweatt, Jeremy J. Day
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/7d938d2a579f49edb66b0941663590e6
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spelling oai:doaj.org-article:7d938d2a579f49edb66b0941663590e62021-12-02T14:38:54ZExtra-coding RNAs regulate neuronal DNA methylation dynamics10.1038/ncomms120912041-1723https://doaj.org/article/7d938d2a579f49edb66b0941663590e62016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12091https://doaj.org/toc/2041-1723DNA methylation in the brain is a dynamic process, but gene-specific regulation of this process is poorly understood. Here, Day and colleagues show that extra-coding RNAs interact with DNA methyltransferases and regulate neuronal DNA methylation to control gene expression in locus-specific manner in neurons.Katherine E. SavellNancy V. N. GallusRhiana C. SimonJordan A. BrownJasmin S. RevannaMary Katherine OsbornEsther Y. SongJohn J. O’MalleyChristian T. StackhouseAllison NorvilHumaira GowherJ. David SweattJeremy J. DayNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Katherine E. Savell
Nancy V. N. Gallus
Rhiana C. Simon
Jordan A. Brown
Jasmin S. Revanna
Mary Katherine Osborn
Esther Y. Song
John J. O’Malley
Christian T. Stackhouse
Allison Norvil
Humaira Gowher
J. David Sweatt
Jeremy J. Day
Extra-coding RNAs regulate neuronal DNA methylation dynamics
description DNA methylation in the brain is a dynamic process, but gene-specific regulation of this process is poorly understood. Here, Day and colleagues show that extra-coding RNAs interact with DNA methyltransferases and regulate neuronal DNA methylation to control gene expression in locus-specific manner in neurons.
format article
author Katherine E. Savell
Nancy V. N. Gallus
Rhiana C. Simon
Jordan A. Brown
Jasmin S. Revanna
Mary Katherine Osborn
Esther Y. Song
John J. O’Malley
Christian T. Stackhouse
Allison Norvil
Humaira Gowher
J. David Sweatt
Jeremy J. Day
author_facet Katherine E. Savell
Nancy V. N. Gallus
Rhiana C. Simon
Jordan A. Brown
Jasmin S. Revanna
Mary Katherine Osborn
Esther Y. Song
John J. O’Malley
Christian T. Stackhouse
Allison Norvil
Humaira Gowher
J. David Sweatt
Jeremy J. Day
author_sort Katherine E. Savell
title Extra-coding RNAs regulate neuronal DNA methylation dynamics
title_short Extra-coding RNAs regulate neuronal DNA methylation dynamics
title_full Extra-coding RNAs regulate neuronal DNA methylation dynamics
title_fullStr Extra-coding RNAs regulate neuronal DNA methylation dynamics
title_full_unstemmed Extra-coding RNAs regulate neuronal DNA methylation dynamics
title_sort extra-coding rnas regulate neuronal dna methylation dynamics
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/7d938d2a579f49edb66b0941663590e6
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