Extra-coding RNAs regulate neuronal DNA methylation dynamics
DNA methylation in the brain is a dynamic process, but gene-specific regulation of this process is poorly understood. Here, Day and colleagues show that extra-coding RNAs interact with DNA methyltransferases and regulate neuronal DNA methylation to control gene expression in locus-specific manner in...
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Nature Portfolio
2016
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oai:doaj.org-article:7d938d2a579f49edb66b0941663590e62021-12-02T14:38:54ZExtra-coding RNAs regulate neuronal DNA methylation dynamics10.1038/ncomms120912041-1723https://doaj.org/article/7d938d2a579f49edb66b0941663590e62016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12091https://doaj.org/toc/2041-1723DNA methylation in the brain is a dynamic process, but gene-specific regulation of this process is poorly understood. Here, Day and colleagues show that extra-coding RNAs interact with DNA methyltransferases and regulate neuronal DNA methylation to control gene expression in locus-specific manner in neurons.Katherine E. SavellNancy V. N. GallusRhiana C. SimonJordan A. BrownJasmin S. RevannaMary Katherine OsbornEsther Y. SongJohn J. O’MalleyChristian T. StackhouseAllison NorvilHumaira GowherJ. David SweattJeremy J. DayNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
spellingShingle |
Science Q Katherine E. Savell Nancy V. N. Gallus Rhiana C. Simon Jordan A. Brown Jasmin S. Revanna Mary Katherine Osborn Esther Y. Song John J. O’Malley Christian T. Stackhouse Allison Norvil Humaira Gowher J. David Sweatt Jeremy J. Day Extra-coding RNAs regulate neuronal DNA methylation dynamics |
description |
DNA methylation in the brain is a dynamic process, but gene-specific regulation of this process is poorly understood. Here, Day and colleagues show that extra-coding RNAs interact with DNA methyltransferases and regulate neuronal DNA methylation to control gene expression in locus-specific manner in neurons. |
format |
article |
author |
Katherine E. Savell Nancy V. N. Gallus Rhiana C. Simon Jordan A. Brown Jasmin S. Revanna Mary Katherine Osborn Esther Y. Song John J. O’Malley Christian T. Stackhouse Allison Norvil Humaira Gowher J. David Sweatt Jeremy J. Day |
author_facet |
Katherine E. Savell Nancy V. N. Gallus Rhiana C. Simon Jordan A. Brown Jasmin S. Revanna Mary Katherine Osborn Esther Y. Song John J. O’Malley Christian T. Stackhouse Allison Norvil Humaira Gowher J. David Sweatt Jeremy J. Day |
author_sort |
Katherine E. Savell |
title |
Extra-coding RNAs regulate neuronal DNA methylation dynamics |
title_short |
Extra-coding RNAs regulate neuronal DNA methylation dynamics |
title_full |
Extra-coding RNAs regulate neuronal DNA methylation dynamics |
title_fullStr |
Extra-coding RNAs regulate neuronal DNA methylation dynamics |
title_full_unstemmed |
Extra-coding RNAs regulate neuronal DNA methylation dynamics |
title_sort |
extra-coding rnas regulate neuronal dna methylation dynamics |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/7d938d2a579f49edb66b0941663590e6 |
work_keys_str_mv |
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