Desmoglein-2-integrin Beta-8 interaction regulates actin assembly in endothelial cells: deregulation in systemic sclerosis.

Desmoglein-2-integrin Beta-8 interaction regulates actin assembly in endothelial cells: deregulation in systemic sclerosis.

<h4>Background</h4>The inability of endothelial cells of patients affected by the diffuse form of Systemic sclerosis (SSc) to perform angiogenesis is a marker of the disease. We previously demonstrated that desmoglein-2 reduction is a major difference between (SSc)-microvascular endothel...

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Main Authors: Betti Giusti, Francesca Margheri, Luciana Rossi, Ilaria Lapini, Alberto Magi, Simona Serratì, Anastasia Chillà, Anna Laurenzana, Lucia Magnelli, Lido Calorini, Francesca Bianchini, Gabriella Fibbi, Rosanna Abbate, Mario Del Rosso
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/7d97f7f03df143acba782aa6b8b587e5
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