Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor

Identification of inhibitors can be accelerated by using the target as a template for ligand formation. Here the authors show that DNA-functionalised magnetic nanoparticles guide templating of G-quadruplex bindingc-MYCinhibitors from an array of building blocks, and can be isolated by magnetic decan...

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Autores principales: Deepanjan Panda, Puja Saha, Tania Das, Jyotirmayee Dash
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7da98346636d440491fe4fd673780c1d
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