Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis

Viruses, including human cytomegalovirus (HCMV), reprogram cellular metabolism using host metabolic regulators to support virus replication. Alternatively, in response to infection, the host can use metabolism to limit virus replication.

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Autores principales:	Lisa M. Wise, Yuecheng Xi, John G. Purdy
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/7daaedca64ee424cb0021770133620c6
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spelling	oai:doaj.org-article:7daaedca64ee424cb0021770133620c62021-11-03T18:56:09ZHypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis2150-751110.1128/mBio.02956-20https://doaj.org/article/7daaedca64ee424cb0021770133620c62021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02956-20https://doaj.org/toc/2150-7511 Viruses, including human cytomegalovirus (HCMV), reprogram cellular metabolism using host metabolic regulators to support virus replication. Alternatively, in response to infection, the host can use metabolism to limit virus replication.Lisa M. WiseYuecheng XiJohn G. PurdyAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Lisa M. Wise Yuecheng Xi John G. Purdy Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis
description	Viruses, including human cytomegalovirus (HCMV), reprogram cellular metabolism using host metabolic regulators to support virus replication. Alternatively, in response to infection, the host can use metabolism to limit virus replication.
format	article
author	Lisa M. Wise Yuecheng Xi John G. Purdy
author_facet	Lisa M. Wise Yuecheng Xi John G. Purdy
author_sort	Lisa M. Wise
title	Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis
title_short	Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis
title_full	Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis
title_fullStr	Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis
title_full_unstemmed	Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis
title_sort	hypoxia-inducible factor 1α (hif1α) suppresses virus replication in human cytomegalovirus infection by limiting kynurenine synthesis
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/7daaedca64ee424cb0021770133620c6
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Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis

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