Implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement

Immune checkpoint blockade antibodies have promising clinical applications, but suffer from severe toxicities and moderate response rates. Here the authors present an electrode-embedded, implantable optical fiber device with both local delivery and tumor impedance measurement capabilities to safely...

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Autores principales:	Ai Lin Chin, Shan Jiang, Eungyo Jang, Liqian Niu, Liwu Li, Xiaoting Jia, Rong Tong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7daf863eae374294b25207133b773047
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spelling	oai:doaj.org-article:7daf863eae374294b25207133b7730472021-12-02T16:35:12ZImplantable optical fibers for immunotherapeutics delivery and tumor impedance measurement10.1038/s41467-021-25391-z2041-1723https://doaj.org/article/7daf863eae374294b25207133b7730472021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25391-zhttps://doaj.org/toc/2041-1723Immune checkpoint blockade antibodies have promising clinical applications, but suffer from severe toxicities and moderate response rates. Here the authors present an electrode-embedded, implantable optical fiber device with both local delivery and tumor impedance measurement capabilities to safely elicit durable anti-tumor immunity.Ai Lin ChinShan JiangEungyo JangLiqian NiuLiwu LiXiaoting JiaRong TongNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ai Lin Chin Shan Jiang Eungyo Jang Liqian Niu Liwu Li Xiaoting Jia Rong Tong Implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement
description	Immune checkpoint blockade antibodies have promising clinical applications, but suffer from severe toxicities and moderate response rates. Here the authors present an electrode-embedded, implantable optical fiber device with both local delivery and tumor impedance measurement capabilities to safely elicit durable anti-tumor immunity.
format	article
author	Ai Lin Chin Shan Jiang Eungyo Jang Liqian Niu Liwu Li Xiaoting Jia Rong Tong
author_facet	Ai Lin Chin Shan Jiang Eungyo Jang Liqian Niu Liwu Li Xiaoting Jia Rong Tong
author_sort	Ai Lin Chin
title	Implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement
title_short	Implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement
title_full	Implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement
title_fullStr	Implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement
title_full_unstemmed	Implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement
title_sort	implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7daf863eae374294b25207133b773047
work_keys_str_mv	AT ailinchin implantableopticalfibersforimmunotherapeuticsdeliveryandtumorimpedancemeasurement AT shanjiang implantableopticalfibersforimmunotherapeuticsdeliveryandtumorimpedancemeasurement AT eungyojang implantableopticalfibersforimmunotherapeuticsdeliveryandtumorimpedancemeasurement AT liqianniu implantableopticalfibersforimmunotherapeuticsdeliveryandtumorimpedancemeasurement AT liwuli implantableopticalfibersforimmunotherapeuticsdeliveryandtumorimpedancemeasurement AT xiaotingjia implantableopticalfibersforimmunotherapeuticsdeliveryandtumorimpedancemeasurement AT rongtong implantableopticalfibersforimmunotherapeuticsdeliveryandtumorimpedancemeasurement
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Implantable optical fibers for immunotherapeutics delivery and tumor impedance measurement

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