High spatial resolution nanoslit SERS for single-molecule nucleobase sensing

Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chang Chen, Yi Li, Sarp Kerman, Pieter Neutens, Kherim Willems, Sven Cornelissen, Liesbet Lagae, Tim Stakenborg, Pol Van Dorpe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/7db9e4ba038b4686a141eb151a141996
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual and incorporated in DNA strands.