High spatial resolution nanoslit SERS for single-molecule nucleobase sensing
Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual...
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Nature Portfolio
2018
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oai:doaj.org-article:7db9e4ba038b4686a141eb151a1419962021-12-02T16:56:37ZHigh spatial resolution nanoslit SERS for single-molecule nucleobase sensing10.1038/s41467-018-04118-72041-1723https://doaj.org/article/7db9e4ba038b4686a141eb151a1419962018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04118-7https://doaj.org/toc/2041-1723Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual and incorporated in DNA strands.Chang ChenYi LiSarp KermanPieter NeutensKherim WillemsSven CornelissenLiesbet LagaeTim StakenborgPol Van DorpeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Chang Chen Yi Li Sarp Kerman Pieter Neutens Kherim Willems Sven Cornelissen Liesbet Lagae Tim Stakenborg Pol Van Dorpe High spatial resolution nanoslit SERS for single-molecule nucleobase sensing |
description |
Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual and incorporated in DNA strands. |
format |
article |
author |
Chang Chen Yi Li Sarp Kerman Pieter Neutens Kherim Willems Sven Cornelissen Liesbet Lagae Tim Stakenborg Pol Van Dorpe |
author_facet |
Chang Chen Yi Li Sarp Kerman Pieter Neutens Kherim Willems Sven Cornelissen Liesbet Lagae Tim Stakenborg Pol Van Dorpe |
author_sort |
Chang Chen |
title |
High spatial resolution nanoslit SERS for single-molecule nucleobase sensing |
title_short |
High spatial resolution nanoslit SERS for single-molecule nucleobase sensing |
title_full |
High spatial resolution nanoslit SERS for single-molecule nucleobase sensing |
title_fullStr |
High spatial resolution nanoslit SERS for single-molecule nucleobase sensing |
title_full_unstemmed |
High spatial resolution nanoslit SERS for single-molecule nucleobase sensing |
title_sort |
high spatial resolution nanoslit sers for single-molecule nucleobase sensing |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/7db9e4ba038b4686a141eb151a141996 |
work_keys_str_mv |
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_version_ |
1718382808339054592 |