High spatial resolution nanoslit SERS for single-molecule nucleobase sensing

Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual...

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Autores principales: Chang Chen, Yi Li, Sarp Kerman, Pieter Neutens, Kherim Willems, Sven Cornelissen, Liesbet Lagae, Tim Stakenborg, Pol Van Dorpe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7db9e4ba038b4686a141eb151a141996
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spelling oai:doaj.org-article:7db9e4ba038b4686a141eb151a1419962021-12-02T16:56:37ZHigh spatial resolution nanoslit SERS for single-molecule nucleobase sensing10.1038/s41467-018-04118-72041-1723https://doaj.org/article/7db9e4ba038b4686a141eb151a1419962018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04118-7https://doaj.org/toc/2041-1723Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual and incorporated in DNA strands.Chang ChenYi LiSarp KermanPieter NeutensKherim WillemsSven CornelissenLiesbet LagaeTim StakenborgPol Van DorpeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chang Chen
Yi Li
Sarp Kerman
Pieter Neutens
Kherim Willems
Sven Cornelissen
Liesbet Lagae
Tim Stakenborg
Pol Van Dorpe
High spatial resolution nanoslit SERS for single-molecule nucleobase sensing
description Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual and incorporated in DNA strands.
format article
author Chang Chen
Yi Li
Sarp Kerman
Pieter Neutens
Kherim Willems
Sven Cornelissen
Liesbet Lagae
Tim Stakenborg
Pol Van Dorpe
author_facet Chang Chen
Yi Li
Sarp Kerman
Pieter Neutens
Kherim Willems
Sven Cornelissen
Liesbet Lagae
Tim Stakenborg
Pol Van Dorpe
author_sort Chang Chen
title High spatial resolution nanoslit SERS for single-molecule nucleobase sensing
title_short High spatial resolution nanoslit SERS for single-molecule nucleobase sensing
title_full High spatial resolution nanoslit SERS for single-molecule nucleobase sensing
title_fullStr High spatial resolution nanoslit SERS for single-molecule nucleobase sensing
title_full_unstemmed High spatial resolution nanoslit SERS for single-molecule nucleobase sensing
title_sort high spatial resolution nanoslit sers for single-molecule nucleobase sensing
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/7db9e4ba038b4686a141eb151a141996
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AT pieterneutens highspatialresolutionnanoslitsersforsinglemoleculenucleobasesensing
AT kherimwillems highspatialresolutionnanoslitsersforsinglemoleculenucleobasesensing
AT svencornelissen highspatialresolutionnanoslitsersforsinglemoleculenucleobasesensing
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AT polvandorpe highspatialresolutionnanoslitsersforsinglemoleculenucleobasesensing
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